Jessica Cooke Bailey, PhD, MA, is Assistant Professor in the Department of Population and Quantitative Health Sciences with CWRU's School of Medicine. Her research has focused on applying sophisticated statistical methods to understand the genetic basis of glaucoma and age-related macular degeneration in European Americans, including the Amish. Dr. Cooke Bailey is now expanding her work to harness the power of electronic health record (EHR) data coupled with genomics and other “omics” data to understand why African Americans are at increased risk for glaucoma compared with other populations. Understanding glaucoma risk factors will begin to address health disparities with the goal of informing treatment options.



Recent Publications

  1. Grunin, M, Kinzy, TG, Cooke Bailey, JN. Note the Nuance-Examining the Association of Alzheimer-Protective APOE Variation With Risk for Age-Related Macular Degeneration. JAMA Ophthalmol 2022; : . PubMed PMID:36394840 .
  2. Waksmunski, AR, Kinzy, TG, Cruz, LA, Nealon, CL, Halladay, CW, Simpson, P, Canania, RL, Anthony, SA, Roncone, DP, Sawicki Rogers, L et al.. Glaucoma Genetic Risk Scores in the Million Veteran Program. Ophthalmology 2022; 129 (11): 1263-1274. PubMed PMID:35718050 .
  3. Nealon, CL, Halladay, CW, Kinzy, TG, Simpson, P, Canania, RL, Anthony, SA, Roncone, DP, Sawicki Rogers, LR, Leber, JN, Dougherty, JM et al.. Development and Evaluation of a Rules-based Algorithm for Primary Open-Angle Glaucoma in the VA Million Veteran Program. Ophthalmic Epidemiol 2022; 29 (6): 640-648. PubMed PMID:34822319 PubMed Central PMC9583190.
  4. Kuan, V, Warwick, A, Hingorani, A, Tufail, A, Cipriani, V, Burgess, S, Sofat, R, International AMD Genomics Consortium (IAMDGC). Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration: A Mendelian Randomization Study. JAMA Ophthalmol 2021; 139 (12): 1299-1306. PubMed PMID:34734970 PubMed Central PMC8569599.
  5. Zebardast, N, Sekimitsu, S, Wang, J, Elze, T, Gharahkhani, P, Cole, BS, Lin, MM, Segrè, AV, Wiggs, JL, International Glaucoma Genetics Consortium et al.. Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank. Ophthalmology 2021; 128 (9): 1300-1311. PubMed PMID:33713785 PubMed Central PMC9134646.
  6. Gharahkhani, P, Jorgenson, E, Hysi, P, Khawaja, AP, Pendergrass, S, Han, X, Ong, JS, Hewitt, AW, Segrè, AV, Rouhana, JM et al.. Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nat Commun 2021; 12 (1): 1258. PubMed PMID:33627673 PubMed Central PMC7904932.
  7. Genetics of Exfoliation Syndrome Partnership, Li, Z, Wang, Z, Lee, MC, Zenkel, M, Peh, E, Ozaki, M, Topouzis, F, Nakano, S, Chan, A et al.. Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye. JAMA 2021; 325 (8): 753-764. PubMed PMID:33620406 PubMed Central PMC7903258.
  8. Waksmunski, AR, Song, YE, Kinzy, TG, Laux, RA, Sewell, J, Fuzzell, D, Fuzzell, S, Miller, S, Wiggs, JL, Pasquale, LR et al.. The GGLEAM Study: Understanding Glaucoma in the Ohio Amish. Int J Environ Res Public Health 2021; 18 (4): . PubMed PMID:33561996 PubMed Central PMC7915874.
  9. Cooke Bailey, JN, Bush, WS, Crawford, DC. Editorial: The Importance of Diversity in Precision Medicine Research. Front Genet 2020; 11 : 875. PubMed PMID:33005167 PubMed Central PMC7479241.
  10. Waksmunski, AR, Grunin, M, Kinzy, TG, Igo, RP Jr, Haines, JL, Cooke Bailey, JN. Statistical driver genes as a means to uncover missing heritability for age-related macular degeneration. BMC Med Genomics 2020; 13 (1): 95. PubMed PMID:32631374 PubMed Central PMC7336430.
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