David C. Kaelber, MD, PhD, MPH

David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System.  Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics.  MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU).  Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area.  Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States.  And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic).  Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time.  This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007.  More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.

Recent Publications

  1. Gao, Z, Tabernacki, T, Davis, PB, Kaelber, DC, Xu, R. Associations of selective serotonin reuptake inhibitors and long COVID risk in patients with depression: a retrospective cohort study. Infection 2025; : . PubMed PMID:40996671 .
  2. Porto, JR, Lavu, MS, Hecht, CJ 2nd, Arnold, KE, Acuña, AJ, Kaelber, DC, Parvizi, J, Kamath, AF. Low-Dose Aspirin: The Safest Prophylactic Approach for Venous Thromboembolism Prevention Following Total Hip Arthroplasty Across All Risk Profiles. J Arthroplasty 2025; : . PubMed PMID:40992597 .
  3. Hoying, D, Kabalan, MJ, Kaelber, DC, Sindwani, R. Comparison of Long-Term Revision Rates and Health Care Utilization Between Standalone Balloon Sinus Dilation and Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients Without Nasal Polyps: Is the Balloon Value Proposition Overinflated? Am J Rhinol Allergy 2025; : 19458924251377259. PubMed PMID:40984002 .
  4. Trinh, I, Shaia, JK, Kaelber, D, Singh, RP, Talcott, KE, Cohen, DA. Prevalence of cardiovascular and cerebrovascular disease in idiopathic intracranial hypertension. Clin Neurol Neurosurg 2025; 258 : 109158. PubMed PMID:40967055 .
  5. Jindal, DA, Hanna, J, Shaia, JK, Markle, J, Rachitskaya, A, Kaelber, DC, Singh, RP, Talcott, KE. Metformin and the Development of Age-Related Macular Degeneration. JAMA Ophthalmol 2025; : . PubMed PMID:40965862 PubMed Central PMC12447287.
  6. Silsby, ZO, Abou Zeki, J, Swensen, A, Rhodes, S, Kaelber, DC, Sheyn, D, Lappen, JR. Adverse Pregnancy Outcomes in Patients with Congenital Uterine Anomalies: Evaluation of a Population Dataset. Am J Perinatol 2025; : . PubMed PMID:40921167 .
  7. Mohan, N, Srivastava, SK, Schulgit, MJ, Nowacki, AS, Kaelber, DC, Sharma, S. Glucagon-Like Peptide-1 Receptor Agonists and Risk of Uveitis. JAMA Ophthalmol 2025; : . PubMed PMID:40875223 PubMed Central PMC12395358.
  8. Issa, R, Calcagno, T, Canova, T, Issa, R, Kaelber, D, Menon, V, Wilson Tang, WH, Griffin, B, Kwon, D, Wang, TKM et al.. Outcomes Associated With SGLT2 Inhibitor Use Following Acute Myocardial Infarction Without Heart Failure: A Propensity-Matched Study. Angiology 2025; : 33197251365016. PubMed PMID:40852947 .
  9. Augusto, SN Jr, Kaelber, DC, Chatterjee, S, Tang, WHW. Sodium Glucose Co-Transporter-2 inhibitors in patients with systemic sclerosis with or without heart failure. Am J Med 2025; : . PubMed PMID:40812492 .
  10. Wang, L, Volkow, ND, Kaelber, DC, Xu, R. Semaglutide or Tirzepatide and Optic Nerve and Visual Pathway Disorders in Type 2 Diabetes. JAMA Netw Open 2025; 8 (8): e2526327. PubMed PMID:40788646 PubMed Central PMC12340659.
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Dr. Kaelber on Twitter

Dr. Kaelber on Twitter

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The Kaelber Lab Website

Curriculum vitae