Jonathan Haines, Ph.D., is a genetic epi­demi­ol­o­gist, Mary W. Shel­don M.D. Pro­fes­sor of Genomic Sci­ences, Chair of Depart­ment of Epi­demi­ol­ogy & Bio­sta­tis­tics, and Direc­tor of the Insti­tute for Com­pu­ta­tional Biol­ogy. Dr. Haines has exten­sive expe­ri­ence in all aspects of genetic epi­demi­ol­ogy with a par­tic­u­lar focus on data ana­lyt­ics. He has applied his exper­tise to numer­ous neu­ro­log­i­cal and oph­thal­mo­log­i­cal dis­or­ders hav­ing located and iden­ti­fied over 20 causal and 200 asso­ci­ated loci. His inter­ests are in adapt­ing and apply­ing sta­tis­ti­cal com­pu­ta­tional meth­ods to bio­med­ical big data.



Recent Publications

  1. Fan, BJ, Chen, X, Sondhi, N, Sharmila, PF, Soumittra, N, Sripriya, S, Sacikala, S, Asokan, R, Friedman, DS, Pasquale, LR et al.. Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus. Invest. Ophthalmol. Vis. Sci. 2018; 59 (6): 2495-2502. PubMed PMID:29847655 PubMed Central PMC5961220.
  2. Hohman, TJ, Dumitrescu, L, Barnes, LL, Thambisetty, M, Beecham, G, Kunkle, B, Gifford, KA, Bush, WS, Chibnik, LB, Mukherjee, S et al.. Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau. JAMA Neurol 2018; : . PubMed PMID:29801024 .
  3. Khawaja, AP, Cooke Bailey, JN, Wareham, NJ, Scott, RA, Simcoe, M, Igo, RP Jr, Song, YE, Wojciechowski, R, Cheng, CY, Khaw, PT et al.. Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma. Nat. Genet. 2018; 50 (6): 778-782. PubMed PMID:29785010 PubMed Central PMC5985943.
  4. Iglesias, AI, Mishra, A, Vitart, V, Bykhovskaya, Y, Höhn, R, Springelkamp, H, Cuellar-Partida, G, Gharahkhani, P, Bailey, JNC, Willoughby, CE et al.. Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nat Commun 2018; 9 (1): 1864. PubMed PMID:29760442 PubMed Central PMC5951816.
  5. Hou, L, Kember, RL, Roach, JC, O'Connell, JR, Craig, DW, Bucan, M, Scott, WK, Pericak-Vance, M, Haines, JL, Crawford, MH et al.. Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations. Sci Rep 2018; 8 (1): 6771. PubMed PMID:29691419 PubMed Central PMC5915589.
  6. Vardarajan, BN, Barral, S, Jaworski, J, Beecham, GW, Blue, E, Tosto, G, Reyes-Dumeyer, D, Medrano, M, Lantigua, R, Naj, A et al.. Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Ann Clin Transl Neurol 2018; 5 (4): 406-417. PubMed PMID:29688227 PubMed Central PMC5899906.
  7. Lancour, D, Naj, A, Mayeux, R, Haines, JL, Pericak-Vance, MA, Schellenberg, GD, Crovella, M, Farrer, LA, Kasif, S. One for all and all for One: Improving replication of genetic studies through network diffusion. PLoS Genet. 2018; 14 (4): e1007306. PubMed PMID:29684019 PubMed Central PMC5933817.
  8. Butkiewicz, M, Blue, E, Leung, F, Jian, X, Marcora, E, Renton, A, Kuzma, A, Wang, LS, Koboldt, D, Haines, JL et al.. Functional Annotation of genomic variants in studies of Late-Onset Alzheimer's Disease. Bioinformatics 2018; : . PubMed PMID:29590295 .
  9. Chung, J, Zhang, X, Allen, M, Wang, X, Ma, Y, Beecham, G, Montine, TJ, Younkin, SG, Dickson, DW, Golde, TE et al.. Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Alzheimers Res Ther 2018; 10 (1): 22. PubMed PMID:29458411 PubMed Central PMC5819208.
  10. Shiga, Y, Akiyama, M, Nishiguchi, KM, Sato, K, Shimozawa, N, Takahashi, A, Momozawa, Y, Hirata, M, Matsuda, K, Yamaji, T et al.. Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Hum. Mol. Genet. 2018; 27 (8): 1486-1496. PubMed PMID:29452408 .
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