Dr. Burchard is Harry Wm. and Diana V. Hind Distinguished Professor in Pharmaceutical Sciences Professor and Vice Chair, Departments of Bioengineering & Therapeutic Sciences and Medicine Director, Center for Genes, Environments & Health at the University of California, San Francisco. Dr. Burchard's laboratory investigates the genetic basis for differences in response to treatment for asthma. Dr. Burchard's laboratory is specifically interested in identifying "ethnic-specific" genetic and biologic risk factors for asthma, asthma severity, and drug responsiveness among US ethnic and racial minority groups as well as developing and applying statistical methods to admixed populations. Dr. Burchard is Principal Investigator of Gene-Environment Studies of Asthma in Hispanic/Latino Children (GALA) I and II among other NIH-funded studies. In March 2015, Dr. Burchard was named to the Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the National Institutes of Health (NIH) Director. More recently, Dr. Burchard was awarded the 2016 American Thoracic Society Innovations in Health Equality - Lifetime Achievement Award.
Recent Publications
- Wu, B, Yang, M, Hu, D, Hochstadt, S, Lee, BH, Lanfear, DE, Witonsky, J, Stemmer, P, Burchard, EG, Ziv, E et al.. Distinct blood transcriptomic profiling underlying asthma establishment and exacerbation. J Allergy Clin Immunol Glob 2026; 5 (2): 100644. PubMed PMID:41660047 PubMed Central PMC12876672.
- Van Buren, E, Zhang, Y, Li, X, Selvaraj, MS, Li, Z, Zhou, H, Palmer, ND, Arnett, DK, Blangero, J, Boerwinkle, E et al.. cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions. Nat Methods 2026; 23 (2): 338-349. PubMed PMID:41476111 .
- Gorla, A, Witonsky, J, Chen, ZJ, Elhawary, JR, Mefford, J, Perez-Garcia, J, Madore, AM, Huntsman, S, Hu, D, Eng, C et al.. Epigenetic patient stratification reveals a sub-endotype of type 2 asthma with altered B-cell response. medRxiv 2025; : . PubMed PMID:40950420 PubMed Central PMC12424920.
- Selvaraj, MS, Li, X, Li, Z, Van Buren, E, Haidermota, S, Postupaka, D, Hornsby, W, Bis, JC, Brody, JA, Cade, BE et al.. Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals. Genome Biol 2025; 26 (1): 273. PubMed PMID:40926209 PubMed Central PMC12418676.
- Martin-Gonzalez, E, Perez-Garcia, J, Martin-Almeida, M, Witonsky, J, Eng, C, Huntsman, S, Hu, D, Lorenzo-Diaz, F, González-Pérez, R, Hernández-Pérez, JM et al.. Multi-Ancestry Epigenome-Wide Association Study of Asthma Exacerbations. Allergy 2026; 81 (1): 263-266. PubMed PMID:40823785 PubMed Central PMC12773656.
- de Santana, MBR, Cruz, ÁA, Teixeira, HMP, Silva, HDS, Abdel-Aziz, MI, Hashimoto, S, Vijverberg, SJH, Herrera-Luis, E, Pino-Yanes, M, Burchard, EG et al.. Chromosome 21 variants tied to severe asthma exacerbations: A genome-wide association study in a Brazilian population. J Allergy Clin Immunol Glob 2025; 4 (3): 100507. PubMed PMID:40677615 PubMed Central PMC12270054.
- Zhang, R, Liu, B, Yang, M, Wu, B, Hochstadt, S, Lanfear, DE, Witonsky, J, Kumar, R, Burchard, EG, Ziv, E et al.. Socioenvironmental factors associated with shrimp allergy and shrimp sensitization in a large and diverse patient population and cohort study from metropolitan Detroit. J Allergy Clin Immunol Glob 2025; 4 (3): 100492. PubMed PMID:40502543 PubMed Central PMC12155558.
- Witonsky, JI, Elhawary, JR, Eng, C, Oh, SS, Salazar, S, Contreras, MG, Medina, V, Secor, EA, Zhang, P, Everman, JL et al.. The PRIMERO birth cohort: Design and baseline characteristics. J Allergy Clin Immunol Glob 2025; 4 (3): 100470. PubMed PMID:40486693 PubMed Central PMC12140944.
- Wu, B, Yang, M, Hu, D, Zhang, R, Liu, B, Hochstadt, S, Lanfear, DE, Witonsky, J, Kumar, R, Hollenbach, JA et al.. HLA variation associated with peanut allergy and anaphylaxis among non-Hispanic Black individuals. J Allergy Clin Immunol Glob 2025; 4 (3): 100485. PubMed PMID:40476093 PubMed Central PMC12139416.
- Zhang, X, Brody, JA, Graff, M, Highland, HM, Chami, N, Xu, H, Wang, Z, Ferrier, KR, Chittoor, G, Josyula, NS et al.. Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. Nat Commun 2025; 16 (1): 3470. PubMed PMID:40216759 PubMed Central PMC11992084.
