David C. Kaelber, MD, PhD, MPH

David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System.  Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics.  MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU).  Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area.  Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States.  And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic).  Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time.  This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007.  More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.

Recent Publications

  1. Lavu, MS, Eghrari, NB, Makineni, PS, Kaelber, DC, Savage, JW, Pelle, DW. Reply to the Letter to the Editor: "Low-Density Lipoprotein Cholesterol and Statin Usage Are Associated With Rates of Pseudarthrosis Following Single-Level Posterior Lumbar Interbody Fusion". Spine (Phila Pa 1976) 2026; : . PubMed PMID:42348827 .
  2. Yazji, IH, Abbass, NJ, Kaelber, DC, Talcott, KE, Singh, RP. The Impact of PCSK9 Inhibitors on Development of Retinal Vascular Occlusions. Am J Ophthalmol 2026; : . PubMed PMID:42341975 .
  3. Moir, JT, Kim, SB, Allan, KC, Kaelber, DC, Singh, RP, Talcott, KE. Demographic and Prevalence Dynamics of Macular Telangiectasia Type 2 From 2015 to 2024. Ophthalmic Surg Lasers Imaging Retina 2026; : 1-6. PubMed PMID:42341259 .
  4. Schulgit, MJ, Bala, S, Bellanda, V, Mohan, N, Arline, A, Kaelber, DC, Lin, P, Mammo, DA, Srivastava, SK, Sharma, S et al.. Associations Between Routine Vaccinations and the Risk of New-Onset Idiopathic Uveitis. Am J Ophthalmol 2026; : . PubMed PMID:42336229 .
  5. Li, SY, Glauser, G, Gonugunta, N, Kaelber, DC, Ben-Israel, D, Muram, S, Bowles, A Jr, Reddy, D, Kelly, ML. Direct oral anticoagulant resumption patterns after traumatic subdural hemorrhage in atrial fibrillation: A multicenter cohort study. Clin Neurol Neurosurg 2026; 269 : 109546. PubMed PMID:42330587 .
  6. Nassief, G, Kaelber, D, Nowacki, AS, Arbesman, J. Genetic predisposition to malignancy confers different outcomes in malignant cutaneous melanoma: A retrospective cohort matched study using TriNetX. J Am Acad Dermatol 2026; : . PubMed PMID:42314938 .
  7. Nugent, JT, Kaelber, DC. Adherence to Guideline-Recommended Testing in Youth With Hypertension: 2014-2024. Pediatrics 2026; : . PubMed PMID:42303272 PubMed Central PMC13278380.
  8. Bank, NC, Mistovich, RJ, Kaelber, DC. More Signal, Less Noise: Enhancing the Methodological Rigor and Clinical Utility of Orthopaedic Aggregated Real-World Data Research. J Bone Joint Surg Am 2026; : . PubMed PMID:42296208 .
  9. Bruiners, N, Ukey, R, Konvinse, KC, Harris, M, Kalaycioglu, M, Yang, JH, Yang, E, Ganapathi, U, Honnen, W, Andrews, T et al.. Antibody repertoire associated with clinically diverse presentations of pediatric SARS-CoV-2 infection. Sci Rep 2026; : . PubMed PMID:42286032 .
  10. Fowler, C, Tlimat, A, Kaelber, DC, Tan, KS, Bliwise, DL, Collop, NA, Pastores, SM, Auckley, DH. Obstructive sleep apnea is associated with a higher 28-day incidence of venous thromboembolism and stroke after total hip arthroplasty. Sleep Breath 2026; 30 (3): . PubMed PMID:42262663 .
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Dr. Kaelber on Twitter

Dr. Kaelber on Twitter

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The Kaelber Lab Website

Curriculum vitae