David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System. Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics. MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU). Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area. Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States. And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic). Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time. This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007. More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.
Recent Publications
- Zhou, T, Zhang, B, Lu, Y, Chen, J, Zang, C, Li, H, Elia, J, Prasad, R, Arnold, J, Avedissian, SN et al.. SSRI/SNRI and long COVID in children and adolescents with neuropsychiatric conditions: a cohort study from the RECOVER Initiative. Nat Ment Health 2026; 4 (8): 1275-1284. PubMed PMID:42564177 PubMed Central PMC13442008.
- Golzar, A, Hamad, CD, Wiener, J, Liu, T, Dajani, AJ, Kaelber, DC, Bernthal, NM, Sheppard, WL, Silva, M, Baghdadi, S et al.. Three-Year Outcomes Following Hip Reconstruction in Cerebral Palsy: A Population-Based Analysis. J Pediatr Orthop 2026; : . PubMed PMID:42559698 .
- Hamad, CD, Wiener, J, Gutierrez, T, Golzar, A, Kittredge, AP, Su, G, Pearce, L, Kaelber, DC, Bernthal, NM, Sheppard, WL et al.. Dysphagia Risk After Single vs Multi-level Anterior Cervical Discectomy and Fusion in Octogenarians: A Propensity Score Matched Analysis. Spine (Phila Pa 1976) 2026; : . PubMed PMID:42550779 .
- Howat, M, Martell, S, Tarabichi, Y, Kaelber, DC, Chen, SS, Freedman, H. Advancing Real-World Evidence Generation: Growth and Lessons Learned from the Early Years of Cosmos. ACI open 2026; 10 (1): e10-e23. PubMed PMID:42523215 PubMed Central PMC13404524.
- Hamad, CD, Wiener, J, Golzar, A, Kaur, H, Henein, C, Kittredge, AP, Su, G, Kaelber, DC, Chan, L, Yeaman, MR et al.. Glucagon-Like Peptide-1 Receptor Agonists and Fragility Fracture Risk in Type 2 Diabetes. JAMA Netw Open 2026; 9 (7): e2625141. PubMed PMID:42496972 PubMed Central PMC13401206.
- Babu, A, Kim, SB, Kaelber, DC, Singh, RP, Rachitskaya, AV, Talcott, KE. Demographic Disparities in the Likelihood of Surgical Repair Following Diagnosis of Rhegmatogenous Retinal Detachment. Am J Ophthalmol 2026; : . PubMed PMID:42480827 .
- Fowler, C, Kaelber, DC, Bliwise, DL, Greer, MK. Rapid Eye Movement Sleep Suppressing Antidepressant Prescription is Associated with Improved Survival in Amyotrophic Lateral Sclerosis. Neurol Sci 2026; 47 (8): . PubMed PMID:42472717 .
- Kim, SB, Zhou, MY, Allan, KC, Kaelber, DC, Babiuch, AS, Singh, RP, Talcott, KE. Evaluation of the Impact of Gamma-Aminobutyric Acid on Diabetic Retinopathy in a Large US Population-Based Cohort. Am J Ophthalmol 2026; 291 : 63-72. PubMed PMID:42435831 .
- Hamad, CD, Wiener, J, Shahamatdar, S, Golzar, A, Liu, T, Su, G, Kittredge, AP, Patel, R, Kaelber, DC, Bernthal, NM et al.. Independent and combined associations of cannabis and nicotine use with postoperative outcomes after cervical and lumbar interbody fusion: a retrospective cohort study. N Am Spine Soc J 2026; 27 : 100915. PubMed PMID:42434720 PubMed Central PMC13352403.
- Xu, K, Kim, SB, Zhao, AH, Kaelber, DC, Singh, RP, Talcott, KE, Mammo, DA. Recombinant Zoster Vaccine Uptake in Patients with Noninfectious Ocular Inflammatory Diseases Receiving Immunosuppression. Am J Ophthalmol 2026; 291 : 57-62. PubMed PMID:42431435 .
