David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System. Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics. MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU). Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area. Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States. And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic). Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time. This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007. More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.
Recent Publications
- Majeed, Z, Issa, R, Calcagno, T, Issa, R, Shukla, N, Prasad, R, Agdamag, AC, Kaelber, DC, Sadler, D, Khorana, AA et al.. Addition of malignancy into the CHADS2/CHA2DS2VASc score: better prediction of stroke risk in individuals with cancer and atrial fibrillation. Cardiooncology 2026; : . PubMed PMID:42237411 .
- Hamad, CD, Nwufo, M, Wiener, J, Liu, T, Olson, TE, Walker, P, Shahamatdar, S, Galoustian, NA, Yusin, N, Golzar, A et al.. Cannabis use increases surgical, medical, and psychosocial complications after lower extremity fracture fixation and shows compounded risk with concurrent nicotine use. Sci Rep 2026; : . PubMed PMID:42236808 .
- Bellanda, V, Schulgit, MJ, Hassan, KA, Kennedy, LB, Barbosa, GCS, Mizuno, Y, Mohan, N, Kaelber, DC, Srivastava, SK, Sharma, S et al.. Immune Checkpoint Inhibitor-Associated Uveitis: Insights from Comparative Analyses Across Malignancies and Drug Classes. Am J Ophthalmol 2026; : . PubMed PMID:42229563 .
- Hanna, F, Abdelmaksoud, A, Dway, A, El-Helbawy, A, Kaelber, DC, Khan, HR, Hammad, N, Mohsen, A, Basta, M. Mechanical Thrombectomy Versus Anticoagulation in Intermediate-Risk Pulmonary Embolism: A Risk-Stratified, Propensity Score-Matched Analysis. Catheter Cardiovasc Interv 2026; : . PubMed PMID:42219798 .
- Hamad, CD, Wiener, J, Liu, T, Golzar, A, Dajani, AJ, Kaelber, DC, Bernthal, NM, Sheppard, WL, Baghdadi, S, Silva, M et al.. Contemporary national treatment patterns for clubfoot relapse-related interventions: a large multi-institutional cohort. BMC Musculoskelet Disord 2026; : . PubMed PMID:42210173 .
- Abbass, NJ, Regueiro, M, Kaelber, DC, Traboulsi, EI, Singh, RP, Talcott, KE. Risk of Ocular Comorbidities in Patients With Inherited Retinal Diseases. Ophthalmic Surg Lasers Imaging Retina 2026; : 1-6. PubMed PMID:42165515 .
- Loften, A, Wang, Q, Farokhnia, M, Kaelber, DC, Volkow, ND, Vendruscolo, LF, Xu, R, Leggio, L. Spironolactone and clinical outcomes in patients with alcohol use disorder and comorbid hypertension: a target trial emulation study. Psychopharmacology (Berl) 2026; : . PubMed PMID:42132959 .
- Kim, SB, Zhou, M, Kaelber, DC, Talcott, KE, Singh, RP. Association between ocular manifestations and incident cardiovascular comorbidities in Ehlers Danlos Syndrome. Eye (Lond) 2026; : . PubMed PMID:42082613 .
- Shaia, JK, Shukla, P, Reed, H, Kaelber, DC, Singh, RP, Talcott, KE. Risk of cerebrovascular and cardiovascular outcomes in patients with an ICD code for ocular migraine. Eye (Lond) 2026; : . PubMed PMID:42056483 .
- Babu, A, Kim, SB, Kaelber, DC, Talcott, KE, Singh, RP. Incidence, Prevalence, and Risk of Retinal Detachment and Tears Up to 10 Years After Phacoemulsification in a Large US Cohort. J Vitreoretin Dis 2026; : 24741264261432182. PubMed PMID:42051908 PubMed Central PMC13111536.
