Dr. McCauley is Associate Professor of Pathology and Dr. John T. Macdonald Foundation Department of Human Genetics at the University of Miami. Dr. McCauley is also Associate Director at the Center for Genome Technology, John P. Hussman Institute for Human Genomics and Director of the Biorepository Core Facility in the Center for Genome Technology at the John P Hussman Institute for Human Genomics. Dr. McCauley is formally trained in human genetics, and his primary interest is to improve the understanding of human disease through disease gene discovery, genomics, and in-depth examination of environmental factors that influence disease outcome. His research focuses on the use of molecular techniques, bioinformatics, and statistical methods to identify genetic variation and to characterize its role in disease susceptibility and outcomes within a variety of human diseases. He has significant experience overseeing biological sample collection, tracking, quality control, genotyping, sequencing and analysis involved in large-scale human genetics projects. Dr. McCauley is a member of several multidisciplinary collaborations with colleagues both nationally and internationally. He has been involved in studying a variety of complex human diseases including autism, Alzheimer disease, stroke, multiple sclerosis, and inflammatory bowel disease.
Recent Publications
- Hupalo, D, McCauley, JL, Gomez, L, Griswold, AJ, Hoher, G, Konidari, I, Lorenzo, J, Parker, GS, Pascual, J, Sandford, AR et al.. The NeuroBioBank whole-genome catalogue of human brain donors with central nervous system disorders. Brain 2026; : . PubMed PMID:41697960 .
- Beecham, AH, McGovern, DPB, Brugger, SW, Davis, MF, Torres, EA, Gomez, L, Li, D, Lopez-Marte, P, Daly, MJ, Stevens, C et al.. Genomic Insights Into Inflammatory Bowel Disease in United States Hispanic Participants: An Ancestry-Focused Study. Gastroenterology 2026; : . PubMed PMID:41661118 .
- Cruz, LA, Liu, S, Miskimen, KL, Cooke Bailey, JN, Kinzy, T, Song, YE, Laux, RA, Miron, P, Ogrocki, PK, Lerner, AJ et al.. Evidence for reduced somatic T-cell receptor sequence diversity profiles among Midwestern Amish in an aging cohort study. medRxiv 2026; : . PubMed PMID:41646721 PubMed Central PMC12870599.
- Ray, NR, Kurup, J, Kumar, A, Rajabli, F, Wang, L, Xu, W, Jin, F, Yilmaz, E, Kizil, C, Bertholim-Nasciben, L et al.. Local genetic correlation analysis of Alzheimer's disease and stroke implicates PHLPP1 as a shared locus in individuals of African ancestry. medRxiv 2025; : . PubMed PMID:41404293 PubMed Central PMC12704622.
- Gudmundsson, S, Singer-Berk, M, Stenton, SL, Goodrich, JK, Wilson, MW, Einson, J, Watts, NA, Genome Aggregation Database Consortium, Lappalainen, T, Rehm, HL et al.. Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database. Nat Commun 2025; 16 (1): 9623. PubMed PMID:41173899 PubMed Central PMC12579199.
- Wu, G, Chen, W, Wuu, J, Jain, A, Myers, J, Cordts, I, Rampersaud, E, Heckmann, JM, Nel, M, Granit, V et al.. Shared burden of ultra-rare genetic variants across a spectrum of motor neuron diseases. Transl Neurodegener 2025; 14 (1): 54. PubMed PMID:41152957 PubMed Central PMC12570777.
- Porras, LM, Rodríguez-Lausell, I, Iglesias-Maldonado, G, Tuliao, EVF, Martínez, G, Leveque, C, Tobon, J, Eloy, R, Belangero, S, Bulik, CM et al.. Functional Genomics Studies of Psychiatric Disorders in Individuals of Latin American Populations: A Scoping Review. Am J Med Genet B Neuropsychiatr Genet 2025; : . PubMed PMID:41014243 PubMed Central PMC12917904.
- Olowoyo, P, Asowata, OJ, Akpa, O, Comeau, ME, Anderson, CD, McCauley, JL, Akinyemi, J, Komolafe, M, Akpalu, A, Arulogun, O et al.. Influence of Ancestral and Geographic Factors on Intracerebral Hemorrhage Risks Among Africans and Americans. Stroke 2025; 56 (12): 3404-3413. PubMed PMID:40988609 PubMed Central PMC12514358.
- Akinyemi, R, Omotoso, O, Kamada, L, Ndetei, D, Cuccaro, M, Akpalu, A, Adams, LD, Sarfo, SF, Njamnshi, AK, Whitehead, P et al.. Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP): A global effort to identify genetic factors in Alzheimer's disease. Alzheimers Dement (N Y) 2025; 11 (3): e70148. PubMed PMID:40861501 PubMed Central PMC12375874.
- Sharma, S, Nagar, SD, Pemu, P, Zuchner, S, SEEC Consortium, Mariño-Ramírez, L, Meller, R, Jordan, IK. Genetic ancestry and population structure in the All of Us Research Program cohort. Nat Commun 2025; 16 (1): 4123. PubMed PMID:40319026 PubMed Central PMC12049439.
