CHUN LI, PH.D.

Assistant Director for Education

Chun Li, Ph.D. is an Asso­ciate Pro­fes­sor of Population and Quantitative Health Sciences.  He has exten­sive expe­ri­ence in sta­tis­ti­cal genet­ics research and genetic data analy­sis.  He is cur­rently work­ing on devel­op­ing meth­ods for detect­ing somatic changes using next-generation sequenc­ing data.  He is also inter­ested in devel­op­ing meth­ods to effi­ciently mine elec­tronic med­ical records.  Active in col­lab­o­ra­tive research, he has been work­ing with inves­ti­ga­tors in var­i­ous fields such as can­cer epi­demi­ol­ogy, clin­i­cal phar­ma­col­ogy, oph­thal­mol­ogy, car­dio­vas­cu­lar dis­ease, autism, type 2 dia­betes, etc.  He has pub­lished in Nature Genet­ics, New Eng­land Jour­nal of Med­i­cine, Blood, Amer­i­can Jour­nal of Human Genet­ics, Bioinformatics, etc.

Affiliations

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Recent Publications

  1. Bentley, AR, Sung, YJ, Brown, MR, Winkler, TW, Kraja, AT, Ntalla, I, Schwander, K, Chasman, DI, Lim, E, Deng, X et al.. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nat. Genet. 2019; 51 (4): 636-648. PubMed PMID:30926973 PubMed Central PMC6467258.
  2. Bien, SA, Su, YR, Conti, DV, Harrison, TA, Qu, C, Guo, X, Lu, Y, Albanes, D, Auer, PL, Banbury, BL et al.. Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer. Hum. Genet. 2019; 138 (4): 307-326. PubMed PMID:30820706 PubMed Central PMC6483948.
  3. de Vries, PS, Brown, MR, Bentley, AR, Sung, YJ, Winkler, TW, Ntalla, I, Schwander, K, Kraja, AT, Guo, X, Franceschini, N et al.. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Am. J. Epidemiol. 2019; : . PubMed PMID:30698716 .
  4. Jiang, X, Finucane, HK, Schumacher, FR, Schmit, SL, Tyrer, JP, Han, Y, Michailidou, K, Lesseur, C, Kuchenbaecker, KB, Dennis, J et al.. Shared heritability and functional enrichment across six solid cancers. Nat Commun 2019; 10 (1): 431. PubMed PMID:30683880 PubMed Central PMC6347624.
  5. Kilpeläinen, TO, Bentley, AR, Noordam, R, Sung, YJ, Schwander, K, Winkler, TW, Jakupović, H, Chasman, DI, Manning, A, Ntalla, I et al.. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nat Commun 2019; 10 (1): 376. PubMed PMID:30670697 PubMed Central PMC6342931.
  6. Huyghe, JR, Bien, SA, Harrison, TA, Kang, HM, Chen, S, Schmit, SL, Conti, DV, Qu, C, Jeon, J, Edlund, CK et al.. Discovery of common and rare genetic risk variants for colorectal cancer. Nat. Genet. 2019; 51 (1): 76-87. PubMed PMID:30510241 PubMed Central PMC6358437.
  7. Schmit, SL, Edlund, CK, Schumacher, FR, Gong, J, Harrison, TA, Huyghe, JR, Qu, C, Melas, M, Van Den Berg, DJ, Wang, H et al.. Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J. Natl. Cancer Inst. 2019; 111 (2): 146-157. PubMed PMID:29917119 .
  8. Feitosa, MF, Kraja, AT, Chasman, DI, Sung, YJ, Winkler, TW, Ntalla, I, Guo, X, Franceschini, N, Cheng, CY, Sim, X et al.. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS ONE 2018; 13 (6): e0198166. PubMed PMID:29912962 PubMed Central PMC6005576.
  9. Zhao, S, Li, CI, Guo, Y, Sheng, Q, Shyr, Y. RnaSeqSampleSize: real data based sample size estimation for RNA sequencing. BMC Bioinformatics 2018; 19 (1): 191. PubMed PMID:29843589 PubMed Central PMC5975570.
  10. Sung, YJ, Winkler, TW, de Las Fuentes, L, Bentley, AR, Brown, MR, Kraja, AT, Schwander, K, Ntalla, I, Guo, X, Franceschini, N et al.. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am. J. Hum. Genet. 2018; 102 (3): 375-400. PubMed PMID:29455858 PubMed Central PMC5985266.
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