David C. Kaelber, MD, PhD, MPH

David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System.  Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics.  MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU).  Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area.  Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States.  And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic).  Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time.  This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007.  More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.

Recent Publications

  1. Tabernacki, T, Wang, L, Kaelber, DC, Xu, R, Berger, NA. Non-Insulin Antidiabetic Agents and Lung Cancer Risk in Drug-Naive Patients with Type 2 Diabetes Mellitus: A Nationwide Retrospective Cohort Study. Cancers (Basel) 2024; 16 (13): . PubMed PMID:39001440 PubMed Central PMC11240387.
  2. Wang, L, Xu, R, Kaelber, DC, Berger, NA. Glucagon-Like Peptide 1 Receptor Agonists and 13 Obesity-Associated Cancers in Patients With Type 2 Diabetes. JAMA Netw Open 2024; 7 (7): e2421305. PubMed PMID:38967919 PubMed Central PMC11227080.
  3. Ashruf, OS, Ashruf, Z, Orozco, Z, Zinter, M, Abu-Arja, R, Yerigeri, K, Haq, IU, Kaelber, DC, Bissler, J, Raina, R et al.. Epidemiology, Risk Factors, and Clinical Outcomes of AKI in Pediatric Hematopoietic Stem Cell Transplant Patients. Kidney360 2024; 5 (6): 802-811. PubMed PMID:38935491 PubMed Central PMC11219119.
  4. Sanghvi, PA, Burkhart, RJ, Belt, NG, Nedder, VJ, Saleh, A, Kaelber, DC, Mistovich, RJ. Epidemiological Trends and Outcomes of Unicompartmental Knee Arthroplasty Among 104 Million Patients in the United States. J Arthroplasty 2024; : . PubMed PMID:38914143 .
  5. Wang, W, Volkow, ND, Berger, NA, Davis, PB, Kaelber, DC, Xu, R. Author Correction: Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population. Nat Commun 2024; 15 (1): 5177. PubMed PMID:38890337 PubMed Central PMC11189541.
  6. Mahajan, UV, Defta, D, Kaelber, DC, Ahuja, SP, Rothstein, BD, Tomei, KL. The association of COVID-19 with increased pediatric ventriculoatrial shunt failures: a national retrospective cohort. J Neurosurg Pediatr 2024; : 1-5. PubMed PMID:38875726 .
  7. Lavu, MS, Porto, JR, Hecht, CJ 2nd, Kaelber, DC, Sculco, PK, Heckmann, ND, Kamath, AF. Five-Year Incidence of Progression to Osteoarthritis and Total Joint Arthroplasty in Patients Prescribed Glucagon-Like Peptide 1 Receptor Agonists. J Arthroplasty 2024; : . PubMed PMID:38857711 .
  8. Wang, W, Volkow, ND, Berger, NA, Davis, PB, Kaelber, DC, Xu, R. Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population. Nat Commun 2024; 15 (1): 4548. PubMed PMID:38806481 PubMed Central PMC11133479.
  9. Lavu, MS, Porto, JR, Hecht, CJ 2nd, Acuña, AJ, Kaelber, DC, Parvizi, J, Kamath, AF. Low-Dose Aspirin Is the Safest Prophylaxis for Prevention of Venous Thromboembolism After Total Knee Arthroplasty Across All Patient Risk Profiles. J Bone Joint Surg Am 2024; 106 (14): 1256-1267. PubMed PMID:38753809 PubMed Central PMC11254562.
  10. Gross, RS, Thaweethai, T, Rosenzweig, EB, Chan, J, Chibnik, LB, Cicek, MS, Elliott, AJ, Flaherman, VJ, Foulkes, AS, Gage Witvliet, M et al.. Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. PLoS One 2024; 19 (5): e0285635. PubMed PMID:38713673 PubMed Central PMC11075869.
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Dr. Kaelber on Twitter

Dr. Kaelber on Twitter

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The Kaelber Lab Website

Curriculum vitae