David C. Kaelber, MD, PhD, MPH

David Kaelber, MD, PhD, MPH, MS, FAAP, FACP, FACMI serves on the Executive Committee of the Cleveland Institute for Computational Biology. Dr. Kaelber is a practicing internist, pediatrician, Vice-President of Health Informatics, and Chief Medical Informatics Officer at the MetroHealth System.  Dr. Kaelber is also Professor in the CWRU Department of Internal Medicine with a secondary appointment in the Departments of Pediatrics and Epidemiology and Biostatistics.  MetroHealth is an integrated health system and a primary teaching site for Case Western Reserve University (CWRU).  Since the late 1990s, MetroHealth has been at the forefront in adopting electronic health records to advance high quality clinical care in the Cleveland area.  Under Dr. Kaelber's leadership, MetroHealth implemented Care Everywhere, a health information exchange program that enables MetroHealth to share patient information with other healthcare systems in the United States.  And, in 2011, Dr. Kaelber was instrumental in the development and launch of MyChart, the personal care health record complement of MetroHealth's EHR (Epic).  Dr. Kaelber's research interests are rooted in pediatric populations where he has used EHR data to identify previously under-diagnosed hypertension patients and to monitor obesity trends over time.  This work earned Dr. Kaelber recognition by the American Heart Association as one of the top ten breakthroughs in cardiovascular and stroke medicine in 2007.  More broadly, Dr. Kaelber's research interests span EHRs, clinical decision support, use of EHRs in chronic disease detection and management, personal health records, and medical informatics.

Recent Publications

  1. Wang, L, Wang, Q, Li, L, Kaelber, DC, Xu, R. GLP-1 receptor agonists and pancreatic cancer risk: target trial emulation using real-world data. J Natl Cancer Inst 2024; : . PubMed PMID:39418202 .
  2. Miller, MG, Terebuh, P, Kaelber, DC, Xu, R, Davis, PB. Characterizing GLP-1 Receptor Agonist Use in Preadolescent and Adolescent Populations. JAMA Netw Open 2024; 7 (10): e2439887. PubMed PMID:39412809 .
  3. Miller, MG, Terebuh, P, Kaelber, DC, Xu, R, Davis, PB. SARS-CoV-2 Infection and New-Onset Type 2 Diabetes Among Pediatric Patients, 2020 to 2022. JAMA Netw Open 2024; 7 (10): e2439444. PubMed PMID:39401034 .
  4. Birabaharan, M, Kaelber, DC, Nizet, V, Zarrinpar, A. Microbiota-derived PPAR-γ signaling and risk of bacterial enteric infection: insight from thiazolidinedione users in a US population-based study. medRxiv 2024; : . PubMed PMID:39398997 PubMed Central PMC11469470.
  5. Upadhyaya, DP, Tarabichi, Y, Prantzalos, K, Ayub, S, Kaelber, DC, Sahoo, SS. Machine learning interpretability methods to characterize the importance of hematologic biomarkers in prognosticating patients with suspected infection. Comput Biol Med 2024; 183 : 109251. PubMed PMID:39393128 .
  6. Swank, Z, Borberg, E, Chen, Y, Senussi, Y, Chalise, S, Manickas-Hill, Z, Yu, XG, Li, JZ, Alter, G, Henrich, TJ et al.. Measurement of circulating viral antigens post-SARS-CoV-2 infection in a multicohort study. Clin Microbiol Infect 2024; : . PubMed PMID:39389851 .
  7. Elangovan, A, Aggarwal, P, Kaelber, DC, Shah, R. RATES OF REPEAT EGD IN NON-DIABETIC ADULTS WITH GLUCAGON-LIKE-PEPTIDE- 1 RECEPTOR AGONIST PRESCRIPTION: A RETROSPECTIVE MATCHED COHORT STUDY. Gastrointest Endosc 2024; : . PubMed PMID:39389433 .
  8. Kuo, A, Yue, S, Kaelber, DC, Li, A. Racial and Ethnic Disparities in Prescription of a Novel Agent in Medical Management of Primary Open-Angle Glaucoma. Ophthalmic Epidemiol 2024; : 1-8. PubMed PMID:39389153 .
  9. Nugent, JT, Kaelber, DC. Utilization of Ambulatory Blood Pressure Monitoring in Children and Adolescents With Hypertension. Pediatrics 2024; : . PubMed PMID:39385675 .
  10. Adelstein, JM, Moyal, AJ, Strony, JT, Burkhart, RJ, Kaelber, DC, Cheng, CW, Gordon, ZL, Furey, CG. Serotonergic Antidepressants are Associated With Higher Rates of Hematoma After Anterior Cervical Spine Surgery: A Large Propensity-matched Cohort Analysis. Spine (Phila Pa 1976) 2024; : . PubMed PMID:39351901 .
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Dr. Kaelber on Twitter

Dr. Kaelber on Twitter

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The Kaelber Lab Website

Curriculum vitae