Symposium Speaker: Blanca E. Himes, PhD

Dr. Blanca Himes is Assistant Professor in the Department of Biostatistics and Epidemiology in the Perelman School of Medicine at the University of Pennsylvania. Dr. Himes is also affiliated with the Graduate Group in Genomics and Computational Biology. As a computational scientist, Dr. Himes’ research interests focus on using biomedical informatics approaches to better understand complex respiratory diseases such as asthma. Among the on-going projects in the Himes lab include understanding the function of disease-associated genes by altering cell-specific transcriptomes, integrating diverse genomic datasets to model cellular transcriptome changes involved in disease, and using geospatial demographic and environmental data to better understand factors that contribute to asthma prevalence and exacerbation. In addition to research, Dr. Himes is active in mentoring students, and she blogs occasionally to address topics posed by young students such as career advice, personal motivation for doing research, and parenthood. Dr. Himes’ research potential and leadership skills have been recognized with the UCSD Sang-keng Ma Memorial Award (2001) and the Harvard-MIT Division of Health Sciences and Technology Student Leadership Award (2007).

Recent Publications

  1. Kan, M, Sun, M, Jiang, X, Diwadkar, AR, Parikh, V, Cao, G, Gebski, E, Jester, W, Lan, B, Panettieri, RA Jr et al.. CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids. Respir Res 2022; 23 (1): 193. PubMed PMID:35902923 PubMed Central PMC9331514.
  2. Joo, J, Mak, ACY, Xiao, S, Sleiman, PM, Hu, D, Huntsman, S, Eng, C, Kan, M, Diwakar, AR, Lasky-Su, JA et al.. Genome-wide association study in minority children with asthma implicates DNAH5 in bronchodilator responsiveness. Sci Rep 2022; 12 (1): 12514. PubMed PMID:35869121 PubMed Central PMC9307508.
  3. Kan, M, Diwadkar, AR, Saxena, S, Shuai, H, Joo, J, Himes, BE. REALGAR: a web app of integrated respiratory omics data. Bioinformatics 2022; : . PubMed PMID:35863045 PubMed Central PMC9477519.
  4. Rizaldi, AA, Xie, S, Hubbard, RA, Himes, BE. Neighborhood Characteristics and COVID-19 Incidence and Mortality in Southeastern Pennsylvania. AMIA Annu Symp Proc 2022; 2022 : 422-431. PubMed PMID:35854746 PubMed Central PMC9285166.
  5. Wang, D, Ho, ES, Cotticelli, MG, Xu, P, Napierala, JS, Hauser, LA, Napierala, M, Himes, BE, Wilson, RB, Lynch, DR et al.. Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich's ataxia. J Lipid Res 2022; 63 (9): 100255. PubMed PMID:35850241 PubMed Central PMC9399481.
  6. Deeney, BT, Cao, G, Orfanos, S, Lee, J, Kan, M, Himes, BE, Parikh, V, Koziol-White, CJ, An, SS, Panettieri, RA Jr et al.. Epinephrine evokes shortening of human airway smooth muscle cells following β2 adrenergic receptor desensitization. Am J Physiol Lung Cell Mol Physiol 2022; 323 (2): L142-L151. PubMed PMID:35787178 PubMed Central PMC9359643.
  7. Christie, C, Xie, S, Diwadkar, AR, Greenblatt, RE, Rizaldi, A, Himes, BE. Consolidated Environmental and Social Data Facilitates Neighborhood-Level Health Studies in Philadelphia. AMIA Annu Symp Proc 2021; 2021 : 305-313. PubMed PMID:35308932 PubMed Central PMC8861730.
  8. Kan, M, Diwadkar, AR, Shuai, H, Joo, J, Wang, AL, Ong, MS, Sordillo, JE, Iribarren, C, Lu, MX, Hernandez-Pacheco, N et al.. Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene. J Allergy Clin Immunol 2022; 149 (6): 1981-1991. PubMed PMID:34971648 PubMed Central PMC9177524.
  9. Martin, JA, Crane-Droesch, A, Lapite, FC, Puhl, JC, Kmiec, TE, Silvestri, JA, Ungar, LH, Kinosian, BP, Himes, BE, Hubbard, RA et al.. Development and validation of a prediction model for actionable aspects of frailty in the text of clinicians' encounter notes. J Am Med Inform Assoc 2021; 29 (1): 109-119. PubMed PMID:34791302 PubMed Central PMC8714261.
  10. Sayed, S, Diwadkar, AR, Dudley, JW, O'Brien, J, Dvorin, D, Kenyon, CC, Himes, BE, Hill, DA, Henrickson, SE. COVID-19 Pandemic-Related Reductions in Pediatric Asthma Exacerbations Corresponded with an Overall Decrease in Respiratory Viral Infections. J Allergy Clin Immunol Pract 2022; 10 (1): 91-99.e12. PubMed PMID:34785388 PubMed Central PMC8590625.
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Dr. Himes on Twitter

Dr. Himes on Twitter

@KAlicea_PhD Que cosa tan tenaz. Estoy de acuerdo con los comentarios de que el video lo deja a uno con lagrimas. Un fuerte abrazo.

The Himes Lab Website

Curriculum vitae