Dr. Burchard is Harry Wm. and Diana V. Hind Distinguished Professor in Pharmaceutical Sciences Professor and Vice Chair, Departments of Bioengineering & Therapeutic Sciences and Medicine Director, Center for Genes, Environments & Health at the University of California, San Francisco. Dr. Burchard's laboratory investigates the genetic basis for differences in response to treatment for asthma. Dr. Burchard's laboratory is specifically interested in identifying "ethnic-specific" genetic and biologic risk factors for asthma, asthma severity, and drug responsiveness among US ethnic and racial minority groups as well as developing and applying statistical methods to admixed populations. Dr. Burchard is Principal Investigator of Gene-Environment Studies of Asthma in Hispanic/Latino Children (GALA) I and II among other NIH-funded studies. In March 2015, Dr. Burchard was named to the Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the National Institutes of Health (NIH) Director. More recently, Dr. Burchard was awarded the 2016 American Thoracic Society Innovations in Health Equality - Lifetime Achievement Award.
- Li, X, Quick, C, Zhou, H, Gaynor, SM, Liu, Y, Chen, H, Selvaraj, MS, Sun, R, Dey, R, Arnett, DK et al.. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies. Nat Genet 2023; 55 (1): 154-164. PubMed PMID:36564505 .
- Beecham, AH, Amezcua, L, Chinea, A, Manrique, CP, Gomez, L, Martinez, A, Beecham, GW, Patsopoulos, NA, Chitnis, T, Weiner, HL et al.. Ancestral risk modification for multiple sclerosis susceptibility detected across the Major Histocompatibility Complex in a multi-ethnic population. PLoS One 2022; 17 (12): e0279132. PubMed PMID:36548255 PubMed Central PMC9778564.
- Xiao, S, Sahasrabudhe, N, Yang, M, Hu, D, Sleiman, P, Hochstadt, S, Cabral, W, Gilliland, F, Gauderman, WJ, Martinez, F et al.. Differences in Self-Reported Food Allergy and Food-Associated Anaphylaxis by Race and Ethnicity Among SAPPHIRE Cohort Participants. J Allergy Clin Immunol Pract 2022; : . PubMed PMID:36403896 .
- Li, Z, Li, X, Zhou, H, Gaynor, SM, Selvaraj, MS, Arapoglou, T, Quick, C, Liu, Y, Chen, H, Sun, R et al.. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nat Methods 2022; 19 (12): 1599-1611. PubMed PMID:36303018 .
- Selvaraj, MS, Li, X, Li, Z, Pampana, A, Zhang, DY, Park, J, Aslibekyan, S, Bis, JC, Brody, JA, Cade, BE et al.. Whole genome sequence analysis of blood lipid levels in >66,000 individuals. Nat Commun 2022; 13 (1): 5995. PubMed PMID:36220816 PubMed Central PMC9553944.
- Sajuthi, SP, Everman, JL, Jackson, ND, Saef, B, Rios, CL, Moore, CM, Mak, ACY, Eng, C, Fairbanks-Mahnke, A, Salazar, S et al.. Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology. Nat Commun 2022; 13 (1): 5806. PubMed PMID:36192399 PubMed Central PMC9530212.
- Herrera-Luis, E, Mak, ACY, Perez-Garcia, J, Martin-Gonzalez, E, Eng, C, Beckman, KB, Huntsman, S, Hu, D, González-Pérez, R, Hernández-Pérez, JM et al.. Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth. Thorax 2022; : . PubMed PMID:36180068 .
- Slob, EMA, Faiz, A, van Nijnatten, J, Vijverberg, SJH, Longo, C, Kutlu, M, Chew, FT, Sio, YY, Herrera-Luis, E, Espuela-Ortiz, A et al.. Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response. Clin Transl Allergy 2022; 12 (8): e12173. PubMed PMID:36036237 PubMed Central PMC9421427.
- Tahir, UA, Katz, DH, Avila-Pachecho, J, Bick, AG, Pampana, A, Robbins, JM, Yu, Z, Chen, ZZ, Benson, MD, Cruz, DE et al.. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun 2022; 13 (1): 4923. PubMed PMID:35995766 PubMed Central PMC9395431.
- Joo, J, Mak, ACY, Xiao, S, Sleiman, PM, Hu, D, Huntsman, S, Eng, C, Kan, M, Diwakar, AR, Lasky-Su, JA et al.. Genome-wide association study in minority children with asthma implicates DNAH5 in bronchodilator responsiveness. Sci Rep 2022; 12 (1): 12514. PubMed PMID:35869121 PubMed Central PMC9307508.