Dr. Burchard is Harry Wm. and Diana V. Hind Distinguished Professor in Pharmaceutical Sciences Professor and Vice Chair, Departments of Bioengineering & Therapeutic Sciences and Medicine Director, Center for Genes, Environments & Health at the University of California, San Francisco. Dr. Burchard's laboratory investigates the genetic basis for differences in response to treatment for asthma. Dr. Burchard's laboratory is specifically interested in identifying "ethnic-specific" genetic and biologic risk factors for asthma, asthma severity, and drug responsiveness among US ethnic and racial minority groups as well as developing and applying statistical methods to admixed populations. Dr. Burchard is Principal Investigator of Gene-Environment Studies of Asthma in Hispanic/Latino Children (GALA) I and II among other NIH-funded studies. In March 2015, Dr. Burchard was named to the Precision Medicine Initiative (PMI) Working Group of the Advisory Committee to the National Institutes of Health (NIH) Director. More recently, Dr. Burchard was awarded the 2016 American Thoracic Society Innovations in Health Equality - Lifetime Achievement Award.
Recent Publications
- de Smith, AJ, Wahlster, L, Jeon, S, Kachuri, L, Black, S, Langie, J, Cato, LD, Nakatsuka, N, Chan, TF, Xia, G et al.. A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children. Cell Genom 2024; 4 (4): 100526. PubMed PMID:38537633 PubMed Central PMC11019360.
- Witonsky, J, Burchard, EG. Race/Ethnicity and Clinical Prediction Algorithms for Childhood Asthma. NEJM Evid 2023; 2 (10): EVIDe2300187. PubMed PMID:38320186 .
- Herrera-Luis, E, Rosa-Baez, C, Huntsman, S, Eng, C, Beckman, KB, LeNoir, MA, Rodriguez-Santana, JR, Villar, J, Laprise, C, Borrell, LN et al.. Novel insights into the whole-blood DNA methylome of asthma in ethnically diverse children and youth. Eur Respir J 2023; 62 (6): . PubMed PMID:37802634 PubMed Central PMC10841414.
- Budu-Aggrey, A, Kilanowski, A, Sobczyk, MK, 23andMe Research Team, Shringarpure, SS, Mitchell, R, Reis, K, Reigo, A, Estonian Biobank Research Team, Mägi, R et al.. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun 2023; 14 (1): 6172. PubMed PMID:37794016 PubMed Central PMC10550990.
- Perez-Garcia, J, Pino-Yanes, M, Plender, EG, Everman, JL, Eng, C, Jackson, ND, Moore, CM, Beckman, KB, Medina, V, Sharma, S et al.. Epigenomic response to albuterol treatment in asthma-relevant airway epithelial cells. Clin Epigenetics 2023; 15 (1): 156. PubMed PMID:37784136 PubMed Central PMC10546710.
- Zhang, X, Brody, JA, Graff, M, Highland, HM, Chami, N, Xu, H, Wang, Z, Ferrier, K, Chittoor, G, Josyula, NS et al.. WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE. medRxiv 2023; : . PubMed PMID:37662265 PubMed Central PMC10473809.
- Recto, K, Kachroo, P, Huan, T, Van Den Berg, D, Lee, GY, Bui, H, Lee, DH, Gereige, J, Yao, C, Hwang, SJ et al.. Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma. EBioMedicine 2023; 95 : 104758. PubMed PMID:37598461 PubMed Central PMC10462855.
- Wong, WJ, Emdin, C, Bick, AG, Zekavat, SM, Niroula, A, Pirruccello, JP, Dichtel, L, Griffin, G, Uddin, MM, Gibson, CJ et al.. Author Correction: Clonal haematopoiesis and risk of chronic liver disease. Nature 2023; 619 (7970): E47. PubMed PMID:37400552 .
- Perez-Garcia, J, Espuela-Ortiz, A, Hernández-Pérez, JM, González-Pérez, R, Poza-Guedes, P, Martin-Gonzalez, E, Eng, C, Sardón-Prado, O, Mederos-Luis, E, Corcuera-Elosegui, P et al.. Human genetics influences microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment. J Allergy Clin Immunol 2023; 152 (3): 799-806.e6. PubMed PMID:37301411 PubMed Central PMC10522330.
- Kachuri, L, Mak, ACY, Hu, D, Eng, C, Huntsman, S, Elhawary, JR, Gupta, N, Gabriel, S, Xiao, S, Keys, KL et al.. Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture. Nat Genet 2023; 55 (6): 952-963. PubMed PMID:37231098 PubMed Central PMC10260401.
