Symposium Speaker: Minoli Perera, PharmD, PhD

Dr. Perera is an Associate Professor in the Department of Pharmacology and Center for Pharmacogenomics at Northwestern University's Feinberg School of Medicine.  With expertise in pharmacokinetics, clinical pharmacology and human genetics, Dr. Perera focuses her research interests on pharmacogenomics in minority populations.  Examples of her work include identifying common genetic variants associated with warfarin dose and identifying genomic risk factors for venous thromboembolism, both in African Americans.  Dr. Perera anticipates that results from these and other multidisciplinary studies will allow the development of an economically sustainable program in clinical pharmacogenetics, including a consult service.  Overall, Dr. Perera's goal is to bring meaningful translation of pharmacogenetics research findings into clinical care, a goal very much consistent with precision medicine.

Recent Publications

  1. Perera, DDBD, Perera, KML, Peiris, DC. A Novel In Silico Benchmarked Pipeline Capable of Complete Protein Analysis: A Possible Tool for Potential Drug Discovery. Biology (Basel) 2021; 10 (11): . PubMed PMID:34827106 PubMed Central PMC8615085.
  2. De, T, Zhang, H, Alarcon, C, Lec, B, Avitia, J, Smithberger, E, Chen, C, Horvath, M, Kwan, S, Young, M et al.. Genetic association of primary nonresponse to anti-TNFα therapy in patients with inflammatory bowel disease. Pharmacogenet Genomics 2022; 32 (1): 1-9. PubMed PMID:34380996 PubMed Central PMC8578201.
  3. Garofano, K, Park, CS, Alarcon, C, Avitia, J, Barbour, A, Diemert, D, Fraser, CM, Friedman, PN, Horvath, A, Rashid, K et al.. Differences in the Platelet mRNA Landscape Portend Racial Disparities in Platelet Function and Suggest Novel Therapeutic Targets. Clin Pharmacol Ther 2021; 110 (3): 702-713. PubMed PMID:34255863 .
  4. Singh, A, Zhong, Y, Nahlawi, L, Park, CS, De, T, Alarcon, C, Perera, MA. Incorporation of DNA methylation into eQTL mapping in African Americans. Pac Symp Biocomput 2021; 26 : 244-255. PubMed PMID:33691021 PubMed Central PMC7958994.
  5. Zhong, Y, De, T, Alarcon, C, Park, CS, Lec, B, Perera, MA. Discovery of novel hepatocyte eQTLs in African Americans. PLoS Genet 2020; 16 (4): e1008662. PubMed PMID:32310939 PubMed Central PMC7192504.
  6. Agrawal, S, Heiss, MS, Fenter, RB, Abramova, TV, Perera, MA, Pacheco, JA, Smith, ME, Rasmussen-Torvik, LJ, George, AL Jr. Impact of CYP2C9-Interacting Drugs on Warfarin Pharmacogenomics. Clin Transl Sci 2020; 13 (5): 941-949. PubMed PMID:32270628 PubMed Central PMC7485961.
  7. Nooruddin, M, Scherr, C, Friedman, P, Subrahmanyam, R, Banagan, J, Moreno, D, Sathyanarayanan, M, Nutescu, E, Jeyaram, T, Harris, M et al.. Why African Americans say "No": A Study of Pharmacogenomic Research Participation. Ethn Dis 2020; 30 (Suppl 1): 159-166. PubMed PMID:32269457 PubMed Central PMC7138442.
  8. Asiimwe, IG, Zhang, EJ, Osanlou, R, Krause, A, Dillon, C, Suarez-Kurtz, G, Zhang, H, Perini, JA, Renta, JY, Duconge, J et al.. Genetic Factors Influencing Warfarin Dose in Black-African Patients: A Systematic Review and Meta-Analysis. Clin Pharmacol Ther 2020; 107 (6): 1420-1433. PubMed PMID:31869433 PubMed Central PMC7217737.
  9. Perera, M. Leaving some behind: the growing gap in precision medicine for minority populations. Expert Rev Precis Med Drug Dev 2019; 4 (1): 3-5. PubMed PMID:31681851 PubMed Central PMC6824595.
  10. Hernandez, W, Danahey, K, Pei, X, Yeo, KJ, Leung, E, Volchenboum, SL, Ratain, MJ, Meltzer, DO, Stranger, BE, Perera, MA et al.. Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation. Pharmacogenomics J 2020; 20 (1): 126-135. PubMed PMID:31506565 PubMed Central PMC7184888.
Search PubMed

Dr. Perera on Twitter

Dr. Perera on Twitter

@hcmefford One of my fav views only bike ride to work.

“Life is hard / not fair” in different languages: 5. Life is not a pony farm (German) 4. Life is not a little feather (Czech) 3. Life is not a request programme (Hungarian) 2. Life is not a field to cross (Russian) 1. The gummy bears are not always evenly divided (Finnish) Retweeted by Dr. Minoli Perera

Me, when it’s time to elegantly serve wine at the dinner table.…

Don’t forget to join the Friday’s PGRN seminar | Nov 19 Friday 8AM PT/11AM ET | Two #PGRNBestPractice talks @drlauraramsey @cincyclinpharm and @aljhydref @LivUni @LivUniLRiG Retweeted by Dr. Minoli Perera

This is what Twitter is for!…

What the....I just can't...the unmitigated gall of people thinking they "own" other people.…

It's not until you work alongside a pharmacist that you realize how much better things are when you work alongside a pharmacist… Retweeted by Dr. Minoli Perera

@calhoujd @CarvillLab Of note...baked good should shared with the hungry neighboring lab...just saying.

@AbePalmer Well that brings back pharmacy school memories.

We are still recruiting for one such position. If you are interested in iPSC and animal models of human adaptations please DM to apply. @eventsWCS #HumanEvol21… Retweeted by Dr. Minoli Perera

Some of the best stuff in the inter webs!…

Fun Halloween trick-or treating with an emphasis on TREATS at the Perera Lab!

test Twitter Media - Fun Halloween trick-or treating with an emphasis on TREATS at the Perera Lab!
test Twitter Media - Fun Halloween trick-or treating with an emphasis on TREATS at the Perera Lab!

@calhoujd When candy is involve we...we are serious!

test Twitter Media - @calhoujd When candy is involve we...we are serious!

The Perera Lab Website

Curriculum vitae