Ignacio Mata, PhD, is Assistant Professor at Cleveland Clinic Lerner College of Medicine. He hold a Bachelor of Science and PhD in Human/Medical Genetics from la Universidad de Oviedo in Asturias, Spain, and he received his PhD in Neurogenetics from Mayo Clinic. Dr. Mata's lab is working towards identifying and understanding the genes that play a role in those diseases that affect the brain (neurological disorders). These include the very well-known Parkinson’s disease (PD), but also other less common disorders such as a form of PD that presents with severe cognitive problems/dementia (PDD) and another type of dementia called Dementia with Lewy Bodies (DLB).
Recent Publications
- Salim, A, Biswas, S, Sonneborn, C, Hogue, O, Hennessy, E, Mays, M, Suneja, A, Ahmed, Z, Mata, IF. Efficacy and Tolerability of Anti-CGRP Monoclonal Antibodies in Patients Aged ≥ 65 Years With Daily or Nondaily Migraine. Neurol Clin Pract 2025; 15 (1): e200373. PubMed PMID:39399553 PubMed Central PMC11464238.
- Pereira, GM, Teixeira-Dos-Santos, D, Soares, NM, Marconi, GA, Friedrich, DC, Saffie Awad, P, Santos-Lobato, BL, Brandão, PRP, Noyce, AJ, Marras, C et al.. A systematic review and meta-analysis of the prevalence of Parkinson's disease in lower to upper-middle-income countries. NPJ Parkinsons Dis 2024; 10 (1): 181. PubMed PMID:39349513 PubMed Central PMC11442769.
- Lázaro-Figueroa, A, Hernández-Medrano, AJ, Ramírez-Pineda, DB, Navarro Cadavid, A, Makarious, M, Foo, JN, Alvarado, CX, Bandres-Ciga, S, Periñan, MT, Global Parkinson's Genetics Program (GP2) et al.. Is SH3GL2 p.G276V the Causal Functional Variant Underlying Parkinson's Disease Risk at this Locus? Mov Disord 2024; : . PubMed PMID:39133574 .
- Junker, J, Lange, LM, Vollstedt, EJ, Roopnarain, K, Doquenia, MLM, Annuar, AA, Avenali, M, Bardien, S, Bahr, N, Ellis, M et al.. Team Science Approaches to Unravel Monogenic Parkinson's Disease on a Global Scale. Mov Disord 2024; 39 (10): 1868-1873. PubMed PMID:39076159 .
- Cook, L, Verbrugge, J, Schwantes-An, TH, Schulze, J, Foroud, T, Hall, A, Marder, KS, Mata, IF, Mencacci, NE, Nance, MA et al.. Parkinson's disease variant detection and disclosure: PD GENEration, a North American study. Brain 2024; 147 (8): 2668-2679. PubMed PMID:39074992 PubMed Central PMC11292896.
- Lorenzo-Betancor, O, Mehta, S, Ramchandra, J, Mumuney, S, Schumacher-Schuh, AF, Cornejo-Olivas, M, Sarapura-Castro, EH, Torres, L, Inca-Martinez, MA, Mazzetti, P et al.. Parkinson's Disease Gene Screening in Familial Cases from Central and South America. Mov Disord 2024; 39 (10): 1843-1855. PubMed PMID:39051491 PubMed Central PMC11490405.
- Jonson, C, Levine, KS, Lake, J, Hertslet, L, Jones, L, Patel, D, Kim, J, Bandres-Ciga, S, Terry, N, Mata, IF et al.. Assessing the lack of diversity in genetics research across neurodegenerative diseases: A systematic review of the GWAS Catalog and literature. Alzheimers Dement 2024; 20 (8): 5740-5756. PubMed PMID:39030740 PubMed Central PMC11350004.
- Salles, PA, Fernández, HH, Mata, IF. Surgicogenomics in GBA1-related Parkinson disease: Is the glass half full or half empty? Parkinsonism Relat Disord 2024; 124 : 106981. PubMed PMID:38714481 .
- Salim, A, Hennessy, E, Sonneborn, C, Hogue, O, Biswas, S, Mays, M, Suneja, A, Ahmed, Z, Mata, IF. Synergism of Anti-CGRP Monoclonal Antibodies and OnabotulinumtoxinA in the Treatment of Chronic Migraine: A Real-World Retrospective Chart Review. CNS Drugs 2024; 38 (6): 481-491. PubMed PMID:38583127 PubMed Central PMC11098928.
- Junker, J, Lange, LM, Vollstedt, EJ, Roopnarain, K, Doquenia, MLM, Annuar, AA, Avenali, M, Bardien, S, Bahr, N, Ellis, M et al.. Understanding monogenic Parkinson's disease at a global scale. medRxiv 2024; : . PubMed PMID:38529492 PubMed Central PMC10962747.
