Ignacio Mata, PhD, is Assistant Professor at Cleveland Clinic Lerner College of Medicine. He hold a Bachelor of Science and PhD in Human/Medical Genetics from la Universidad de Oviedo in Asturias, Spain, and he received his PhD in Neurogenetics from Mayo Clinic. Dr. Mata's lab is working towards identifying and understanding the genes that play a role in those diseases that affect the brain (neurological disorders). These include the very well-known Parkinson’s disease (PD), but also other less common disorders such as a form of PD that presents with severe cognitive problems/dementia (PDD) and another type of dementia called Dementia with Lewy Bodies (DLB).
Recent Publications
- Atterling Brolin, K, Lange, LM, Navarro-Jones, E, Jasaityte, S, Ye Beh, Y, Fang, ZH, Iwaki, H, Jones, L, Klein, C, Kleinz, T et al.. Bridging Genetics and Precision Medicine in Parkinson's Disease through GP2. medRxiv 2026; : . PubMed PMID:42051573 PubMed Central PMC13119358.
- Landoulsi, Z, Sreelatha, AAK, Kuznetsov, N, Schulte, C, Bobbili, DR, Montanucci, L, Leu, C, Niestroj, LM, Hassanin, E, Domenighetti, C et al.. Genome-wide association study of copy number variations in Parkinson's disease. NPJ Parkinsons Dis 2026; : . PubMed PMID:42009659 .
- Chaparro-Solano, HM, Teixeira-Dos-Santos, D, Waldo, E, Leal, TP, Inca-Martinez, M, Alcauter, S, Medina-Rivera, A, Ruiz-Contreras, AE, Cornejo-Olivas, M, Mejia-Rojas, K et al.. Levodopa-Induced dyskinesia in Latin America: Prevalence and associated clinical factors in the LARGE-PD cohort. J Parkinsons Dis 2026; : 1877718X261431204. PubMed PMID:41995451 .
- Sun, W, Schulte, C, Gasser, T, Tan, M, Global Parkinson’s Genetic Program (GP2). Author Correction: TMEM175, SCARB2 and CTSB associations with Parkinson's disease risk across populations. NPJ Parkinsons Dis 2026; 12 (1): . PubMed PMID:41974742 PubMed Central PMC13077031.
- Step, K, Hernández, CF, Khani, M, Eltaraifee, E, Hernández-Medrano, AJ, Kung, PJ, Ostrožovičová, M, Zirra, A, Pérez-Palma, E, Mencacci, NE et al.. Genome-Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology. Mov Disord 2026; : . PubMed PMID:41808632 .
- Step, K, Ndong Sima, CAA, Grant, S, Kim, JJ, Waldo, E, Bardien, S, Mata, IF, Global Parkinson’s Genetics Program (GP2). Polygenic risk scores and Parkinson's disease in South Africa advancing ancestry informed disease prediction. PLoS Genet 2026; 22 (3): e1012064. PubMed PMID:41801886 PubMed Central PMC12987585.
- da Silva, PHP, Abreu, JS, Gomes, RSG, Oliveira, HKA, Schuh, AFS, Mata, IF, Santos-Lobato, BL. Revisiting the Association of Pesticide Exposure and Parkinson's Disease: Systematic Review and Meta-Analysis. Environ Toxicol 2026; : . PubMed PMID:41566858 .
- Step, K, Waldo, E, Leal, TP, Mendes, M, Bardien, S, Mata, IF. Insights into X-Linked Susceptibility to Parkinson's Disease in the South African Population. medRxiv 2025; : . PubMed PMID:41480044 PubMed Central PMC12755251.
- Step, K, Madula, L, Kuznetsov, N, Maasdorp, E, Carr, J, van Coller, R, Mata, IF, Bardien, S. Comprehensive genetic screening of the South African Parkinson's disease study collection using the NeuroBooster array. medRxiv 2025; : . PubMed PMID:41445612 PubMed Central PMC12723977.
- Sun, W, Schulte, C, Gasser, T, Tan, M, Global Parkinson’s Genetic Program (GP2). TMEM175, SCARB2 and CTSB associations with Parkinson's disease risk across populations. NPJ Parkinsons Dis 2025; 11 (1): 348. PubMed PMID:41331295 PubMed Central PMC12678402.
