Ignacio Mata, PhD, is Assistant Professor at Cleveland Clinic Lerner College of Medicine. He hold a Bachelor of Science and PhD in Human/Medical Genetics from la Universidad de Oviedo in Asturias, Spain, and he received his PhD in Neurogenetics from Mayo Clinic. Dr. Mata's lab is working towards identifying and understanding the genes that play a role in those diseases that affect the brain (neurological disorders). These include the very well-known Parkinson’s disease (PD), but also other less common disorders such as a form of PD that presents with severe cognitive problems/dementia (PDD) and another type of dementia called Dementia with Lewy Bodies (DLB).
Recent Publications
- Lange, LM, Fang, ZH, Makarious, MB, Kuznetsov, N, Atterling Brolin, K, Ballard, S, Bardien, S, Doquenia, ML, Heutink, P, Houlden, H et al.. Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications. Lancet Neurol 2026; 25 (8): 741-754. PubMed PMID:42456684 .
- Reyes-Pérez, P, Hor, JW, Toh, TS, Sanyaolu, AO, Pantazis, CB, Leal, TP, Yeboah, S, Bandres-Ciga, S, Morris, HR, Makarious, MB et al.. Exploring MAPT-containing H1 and H2 haplotypes in Parkinson's disease across diverse populations. NPJ Parkinsons Dis 2026; : . PubMed PMID:42342696 .
- Wu, LY, du Toit, T, Georgiades, T, Stafford, EJ, Levine, K, Fang, ZH, Jasaityte, S, Martinez, AG, Cullinane, P, De Pablo-Fernandez, E et al.. Pathology and Genetics in a Global Cohort of Parkinsonian Disorders. JAMA Neurol 2026; : . PubMed PMID:42258190 PubMed Central PMC13247843.
- Correa, LVS, do Nascimento, AM, Santos-Lobato, BL, Chaparro-Solano, HM, Mata, IF, Tumas, V. Placebo Effect in Levodopa-Induced Dyskinesia: A Systematic Review and Meta-Analysis. Mov Disord Clin Pract 2026; : . PubMed PMID:42185744 PubMed Central PMC13339215.
- Flores-Ocampo, V, Zirra, A, Tay, YW, van Midden, V, Mata, IF, Noyce, AJ, Periñan, MT, Global Parkinson's Genetics Program (GP2). The Global Parkinson's Genetics Program (GP2): Advancing genetic discovery and capacity building worldwide. J Parkinsons Dis 2026; 16 (4): 617-628. PubMed PMID:42159407 .
- Atterling Brolin, K, Lange, LM, Navarro-Jones, E, Jasaityte, S, Ye Beh, Y, Fang, ZH, Iwaki, H, Jones, L, Klein, C, Kleinz, T et al.. Bridging Genetics and Precision Medicine in Parkinson's Disease through GP2. medRxiv 2026; : . PubMed PMID:42051573 PubMed Central PMC13119358.
- Landoulsi, Z, Sreelatha, AAK, Kuznetsov, N, Schulte, C, Bobbili, DR, Montanucci, L, Leu, C, Niestroj, LM, Hassanin, E, Domenighetti, C et al.. Genome-wide association study of copy number variations in Parkinson's disease. NPJ Parkinsons Dis 2026; 12 (1): . PubMed PMID:42009659 PubMed Central PMC13323976.
- Chaparro-Solano, HM, Teixeira-Dos-Santos, D, Waldo, E, Leal, TP, Inca-Martinez, M, Alcauter, S, Medina-Rivera, A, Ruiz-Contreras, AE, Cornejo-Olivas, M, Mejia-Rojas, K et al.. Levodopa-Induced dyskinesia in Latin America: Prevalence and associated clinical factors in the LARGE-PD cohort. J Parkinsons Dis 2026; 16 (4): 723-735. PubMed PMID:41995451 .
- Sun, W, Schulte, C, Gasser, T, Tan, M, Global Parkinson’s Genetic Program (GP2). Author Correction: TMEM175, SCARB2 and CTSB associations with Parkinson's disease risk across populations. NPJ Parkinsons Dis 2026; 12 (1): . PubMed PMID:41974742 PubMed Central PMC13077031.
- Step, K, Hernández, CF, Khani, M, Eltaraifee, E, Hernández-Medrano, AJ, Kung, PJ, Ostrožovičová, M, Zirra, A, Pérez-Palma, E, Mencacci, NE et al.. Genome-Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology. Mov Disord 2026; 41 (5): 1128-1140. PubMed PMID:41808632 PubMed Central PMC13206428.
