
Dr. Sedor is Professor of Physiology and Biophysics and Director of the Case Center for the Study of Kidney Biology and Disease at Case Western Reserve University; Professor of Molecular Medicine at Cleveland Clinic Lerner College of Medicine; and Ray W. Gifford, M.D. Endowed Chair in Kidney Research at the Glickman Urology & Kidney Institute. Dr. Sedor is board certified in internal medicine and nephrology and is a practicing physician scientist as Staff of the Department of Nephrology and Hypertension at Cleveland Clinic. Dr. Sedor's research interests focus on progressive kidney disease mechanisms, and his research team's goals are to define clinical, cellular, and genetic bases of kidney disease to identify new therapies and diagnostic tests. Dr. Sedor is a leader and active member of several research consortia, include the Nephrotic Syndrome Study Network (NEPTUNE) and Cure Glomerulonephropathy (CureGN). Dr. Sedor is also a co-Principal Investigator of the Cleveland ascertainment site for the NIDDK-supported Kidney Precision Medicine Project (KPMP), a national collaborative effort that aims to create a kidney tissue atlas, define disease subgroups, and identify critical cells, pathways, and targets for novel therapies. Dr. Sedor's current investigator-initiated projects focus on kidney disease attributable to APOL1 renal risk variants, the major genetic contributors to observed racial disparities in chronic kidney disease, and use of electronic health records to identify diabetic patients with renal complications.