Previous Positions
Crawford Graduate Student (2009-2014)
Post-Doctoral Fellow, Department of Human Genetics, University of Michigan (2014-2017)
Bioinformatics Staff Scientist, Autism & Developmental Medicine Institute (ADMI), Geisinger Health System (2017-2019)
Current Position
Assistant Professor, Geisinger Medical Center (2020-present)
Research Interests
Matt's graduate research was focused on the utilization of an EMR-linked biorepository for pharmacogenetic studies on a wide range of drugs including clopidogrel, warfarin, calcineurin-inhibitors, and statins. Matt's current research interests include the genetics of drug efficacy and adverse drug response, data-mining clinical data from electronic medical records, functional variation in pharmacogenes, and phenome-wide association studies. Matt's research skills include the design of pharmacogenomic studies in an EMR-based biobank, genetic analysis of SNP data and rare variants, and experience with large datasets.
Recent Publications
- Berry, ASF, Finucane, BM, Myers, SM, Abril, A, Kirchner, HL, Ledbetter, DH, Martin, CL, Oetjens, MT. Association of Supernumerary Sex Chromosome Aneuploidies With Venous Thromboembolism. JAMA 2023; 329 (3): 235-243. PubMed PMID:36648468 PubMed Central PMC9857362.
- Savatt, JM, Oetjens, MT, Myers, SM, Finucane, BM. Response to van Riel et al. Genet Med 2023; 25 (1): 161-163. PubMed PMID:36609148 .
- Shimelis, H, Oetjens, MT, Walsh, LK, Wain, KE, Znidarsic, M, Myers, SM, Finucane, BM, Ledbetter, DH, Martin, CL. Prevalence and Penetrance of Rare Pathogenic Variants in Neurodevelopmental Psychiatric Genes in a Health Care System Population. Am J Psychiatry 2023; 180 (1): 65-72. PubMed PMID:36475376 PubMed Central PMC10017070.
- Praveen, K, Patel, GC, Gurski, L, Ayer, AH, Persaud, T, Still, MD, Miloscio, L, Van Zyl, T, Di Gioia, SA, Brumpton, B et al.. ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma. Commun Biol 2022; 5 (1): 1051. PubMed PMID:36192519 PubMed Central PMC9529959.
- Praveen, K, Dobbyn, L, Gurski, L, Ayer, AH, Staples, J, Mishra, S, Bai, Y, Kaufman, A, Moscati, A, Benner, C et al.. Population-scale analysis of common and rare genetic variation associated with hearing loss in adults. Commun Biol 2022; 5 (1): 540. PubMed PMID:35661827 PubMed Central PMC9166757.
- Savatt, JM, Shimelis, H, Moreno-De-Luca, A, Strande, NT, Oetjens, MT, Ledbetter, DH, Martin, CL, Myers, SM, Finucane, BM. Frequency of truncating FLCN variants and Birt-Hogg-Dubé-associated phenotypes in a health care system population. Genet Med 2022; 24 (9): 1857-1866. PubMed PMID:35639097 PubMed Central PMC9703446.
- Kousathanas, A, Pairo-Castineira, E, Rawlik, K, Stuckey, A, Odhams, CA, Walker, S, Russell, CD, Malinauskas, T, Wu, Y, Millar, J et al.. Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature 2022; 607 (7917): 97-103. PubMed PMID:35255492 PubMed Central PMC9259496.
- Jurgens, SJ, Choi, SH, Morrill, VN, Chaffin, M, Pirruccello, JP, Halford, JL, Weng, LC, Nauffal, V, Roselli, C, Hall, AW et al.. Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank. Nat Genet 2022; 54 (3): 240-250. PubMed PMID:35177841 PubMed Central PMC8930703.
- Finucane, B, Oetjens, MT, Johns, A, Myers, SM, Fisher, C, Habegger, L, Maxwell, EK, Reid, JG, Ledbetter, DH, Kirchner, HL et al.. Medical manifestations and health care utilization among adult MyCode participants with neurodevelopmental psychiatric copy number variants. Genet Med 2022; 24 (3): 703-711. PubMed PMID:34906480 PubMed Central PMC8901449.
- Deaton, AM, Parker, MM, Ward, LD, Flynn-Carroll, AO, BonDurant, L, Hinkle, G, Akbari, P, Lotta, LA, Regeneron Genetics Center, DiscovEHR Collaboration et al.. Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes. Sci Rep 2021; 11 (1): 21565. PubMed PMID:34732801 PubMed Central PMC8566487.