Past Crew Member: Matthew T. Oetjens, PhD, MS

Previous Positions

Crawford Graduate Student (2009-2014)

Post-Doctoral Fellow, Department of Human Genetics, University of Michigan (2014-2017)

Bioinformatics Staff Scientist, Autism & Developmental Medicine Institute (ADMI), Geisinger Health System (2017-2019)

Current Position

Assistant Professor, Geisinger Medical Center (2020-present)

Research Interests

Matt's graduate research was focused on the utilization of an EMR-linked biorepository for pharmacogenetic studies on a wide range of drugs including clopidogrel, warfarin, calcineurin-inhibitors, and statins.  Matt's current research interests include the genetics of drug efficacy and adverse drug response, data-mining clinical data from electronic medical records, functional variation in pharmacogenes, and phenome-wide association studies.  Matt's research skills include the design of pharmacogenomic studies in an EMR-based biobank, genetic analysis of SNP data and rare variants, and experience with large datasets.

Recent Publications

  1. Berry, ASF, Finucane, BM, Myers, SM, Abril, A, Kirchner, HL, Ledbetter, DH, Martin, CL, Oetjens, MT. Association of Supernumerary Sex Chromosome Aneuploidies With Venous Thromboembolism. JAMA 2023; 329 (3): 235-243. PubMed PMID:36648468 .
  2. Savatt, JM, Oetjens, MT, Myers, SM, Finucane, BM. Response to van Riel et al. Genet Med 2023; 25 (1): 161-163. PubMed PMID:36609148 .
  3. Shimelis, H, Oetjens, MT, Walsh, LK, Wain, KE, Znidarsic, M, Myers, SM, Finucane, BM, Ledbetter, DH, Martin, CL. Prevalence and Penetrance of Rare Pathogenic Variants in Neurodevelopmental Psychiatric Genes in a Health Care System Population. Am J Psychiatry 2023; 180 (1): 65-72. PubMed PMID:36475376 .
  4. Praveen, K, Patel, GC, Gurski, L, Ayer, AH, Persaud, T, Still, MD, Miloscio, L, Van Zyl, T, Di Gioia, SA, Brumpton, B et al.. ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma. Commun Biol 2022; 5 (1): 1051. PubMed PMID:36192519 PubMed Central PMC9529959.
  5. Praveen, K, Dobbyn, L, Gurski, L, Ayer, AH, Staples, J, Mishra, S, Bai, Y, Kaufman, A, Moscati, A, Benner, C et al.. Population-scale analysis of common and rare genetic variation associated with hearing loss in adults. Commun Biol 2022; 5 (1): 540. PubMed PMID:35661827 PubMed Central PMC9166757.
  6. Savatt, JM, Shimelis, H, Moreno-De-Luca, A, Strande, NT, Oetjens, MT, Ledbetter, DH, Martin, CL, Myers, SM, Finucane, BM. Frequency of truncating FLCN variants and Birt-Hogg-Dubé-associated phenotypes in a health care system population. Genet Med 2022; 24 (9): 1857-1866. PubMed PMID:35639097 PubMed Central PMC9703446.
  7. Kousathanas, A, Pairo-Castineira, E, Rawlik, K, Stuckey, A, Odhams, CA, Walker, S, Russell, CD, Malinauskas, T, Wu, Y, Millar, J et al.. Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature 2022; 607 (7917): 97-103. PubMed PMID:35255492 PubMed Central PMC9259496.
  8. Jurgens, SJ, Choi, SH, Morrill, VN, Chaffin, M, Pirruccello, JP, Halford, JL, Weng, LC, Nauffal, V, Roselli, C, Hall, AW et al.. Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank. Nat Genet 2022; 54 (3): 240-250. PubMed PMID:35177841 PubMed Central PMC8930703.
  9. Finucane, B, Oetjens, MT, Johns, A, Myers, SM, Fisher, C, Habegger, L, Maxwell, EK, Reid, JG, Ledbetter, DH, Kirchner, HL et al.. Medical manifestations and health care utilization among adult MyCode participants with neurodevelopmental psychiatric copy number variants. Genet Med 2022; 24 (3): 703-711. PubMed PMID:34906480 PubMed Central PMC8901449.
  10. Deaton, AM, Parker, MM, Ward, LD, Flynn-Carroll, AO, BonDurant, L, Hinkle, G, Akbari, P, Lotta, LA, Regeneron Genetics Center, DiscovEHR Collaboration et al.. Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes. Sci Rep 2021; 11 (1): 21565. PubMed PMID:34732801 PubMed Central PMC8566487.
Search PubMed