Past Crew Member: Janina M. Jeff, PhD, MS

Previous Positions

Crawford Graduate Student (2007-2012)

Crawford Post-Doctoral Fellow (2012-2013)

Post-Doctoral Fellow at the Icahn School of Medicine at Mount Sinai (2013-2015)

Current Position

Global Bioinformatics Specialist, Illumina (2015-present)

In Those Genes podcast, founder (2019-present) and ASHG Advocacy Awardee (2020)

Research Interests

As a genetic epidemiologist, Janina has an interest in identifying genetic variants that explain disease disparities observed across populations.  Janina has applied her interests to several common human diseases and traits including quantitative cardiovascular traits, anthropometric traits, hematological traits, reproductive outcomes, chronic kidney disease, type 2 diabetes, and pharmacogenomics in highly structured admixed populations such as African Americans and Hispanics.  Janina has developed approaches to extract data from a series of clinical data warehouses to define novel clinical phenotypes, for example extracting real-time physiologic response to short acting catacholamines administered during surgery for pharmacogenomic studies.

Recent Publications

  1. Wang, B, Zhao, J, Liu, S, Feng, J, Luo, Y, He, X, Wang, Y, Ge, F, Wang, J, Ye, B et al.. ACE2 Decoy Receptor Generated by High-throughput Saturation Mutagenesis Efficiently Neutralizes SARS-CoV-2 and Its Prevalent Variants. Emerg Microbes Infect 2022; : 1-0. PubMed PMID:35587428 .
  2. Wiley, K, Findley, L, Goldrich, M, Rakhra-Burris, TK, Stevens, A, Williams, P, Bult, CJ, Chisholm, R, Deverka, P, Ginsburg, GS et al.. A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources. J Am Med Inform Assoc 2022; : . PubMed PMID:35485600 .
  3. Wenric, S, Jeff, JM, Joseph, T, Yee, MC, Belbin, GM, Owusu Obeng, A, Ellis, SB, Bottinger, EP, Gottesman, O, Levin, MA et al.. Rapid response to the alpha-1 adrenergic agent phenylephrine in the perioperative period is impacted by genomics and ancestry. Pharmacogenomics J 2021; 21 (2): 174-189. PubMed PMID:33168928 PubMed Central PMC7997806.
  4. Pendergrass, SA, Buyske, S, Jeff, JM, Frase, A, Dudek, S, Bradford, Y, Ambite, JL, Avery, CL, Buzkova, P, Deelman, E et al.. A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans. PLoS One 2019; 14 (12): e0226771. PubMed PMID:31891604 PubMed Central PMC6938343.
  5. Edwards, TL, Giri, A, Hellwege, JN, Hartmann, KE, Stewart, EA, Jeff, JM, Bray, MJ, Pendergrass, SA, Torstenson, ES, Keaton, JM et al.. A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids. Front Genet 2019; 10 : 511. PubMed PMID:31249589 PubMed Central PMC6582231.
  6. Wojcik, GL, Graff, M, Nishimura, KK, Tao, R, Haessler, J, Gignoux, CR, Highland, HM, Patel, YM, Sorokin, EP, Avery, CL et al.. Genetic analyses of diverse populations improves discovery for complex traits. Nature 2019; 570 (7762): 514-518. PubMed PMID:31217584 PubMed Central PMC6785182.
  7. Fernández-Rhodes, L, Malinowski, JR, Wang, Y, Tao, R, Pankratz, N, Jeff, JM, Yoneyama, S, Carty, CL, Setiawan, VW, Le Marchand, L et al.. The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis. PLoS One 2018; 13 (7): e0200486. PubMed PMID:30044860 PubMed Central PMC6059436.
  8. Hellwege, JN, Jeff, JM, Wise, LA, Gallagher, CS, Wellons, M, Hartmann, KE, Jones, SF, Torstenson, ES, Dickinson, S, Ruiz-Narváez, EA et al.. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet 2017; 136 (11-12): 1497-1498. PubMed PMID:28975356 PubMed Central PMC5909202.
  9. Belbin, GM, Odgis, J, Sorokin, EP, Yee, MC, Kohli, S, Glicksberg, BS, Gignoux, CR, Wojcik, GL, Van Vleck, T, Jeff, JM et al.. Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system. Elife 2017; 6 : . PubMed PMID:28895531 PubMed Central PMC5595434.
  10. Hellwege, JN, Jeff, JM, Wise, LA, Gallagher, CS, Wellons, M, Hartmann, KE, Jones, SF, Torstenson, ES, Dickinson, S, Ruiz-Narváez, EA et al.. A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet 2017; 136 (10): 1363-1373. PubMed PMID:28836065 PubMed Central PMC5628188.
Search PubMed

Janina on Twitter

We STILL growing the ITG fam! Everyone, meet Warner Meadows! He’s our brand new composer for the show! 🚀 Warner has been working on the last few episode of season 2 and we can’t wait to see what else he has in store for season 3! Let’s give him a warm welcome! 🧬📣

test Twitter Media - We STILL growing the ITG fam! Everyone, meet Warner Meadows! 
He’s our brand new composer for the show! 
🚀
Warner has been working on the last few episode of season 2 and we can’t wait to see what else he has in store for season 3! Let’s give him a warm welcome! 🧬📣 https://t.co/kUhQevmXaO
test Twitter Media - We STILL growing the ITG fam! Everyone, meet Warner Meadows! 
He’s our brand new composer for the show! 
🚀
Warner has been working on the last few episode of season 2 and we can’t wait to see what else he has in store for season 3! Let’s give him a warm welcome! 🧬📣 https://t.co/kUhQevmXaO

🧬 WHAT WAST? 🧬 Waist to hip ratio (WHR) is the size of your waist as compared to the size of your hips. The estimated total amount of it is attributed to 30-70% genetics. Due to lack of research it is unclear as to whether WHR varies between populations.

🧬 HOWS THE WEATHER UP THERE? 🧬 Height can influence body shape. Those that are taller might have lower waist to height ratios (lean), & those that are shorter have higher waist to height ratios (stout) To date, we estimate that genetics can explain up to 18.5% of body shapes

🧬 THE STUDY OF ANTHROPOMETRY 🧬 Some of the most common traits used to describe body shape are: height, waist to hip ratio, fat distribution, and BMl.

🧬 THE STUDY OF ANTHROPOMETRY 🧬 Somatotype is the scientific term used to describe body shape. Scientists describe body shape as the measurements & proportions of our bodies. Anthropometry is the scientific study of body shape.

We’ve got our Henrietta Facts from our final episode of the season, “Baby Got Black” hot and ready for y’all! ❤️‍🔥🔥🧬 We hope you enjoy this first batch…more is coming your way! Don’t forget: You can listen to the full episode by clicking the link in the bio!❤️🙏🏾🧬 (1/7)

test Twitter Media - We’ve got our Henrietta Facts from our final episode of the season, “Baby Got Black” hot and ready for y’all! ❤️‍🔥🔥🧬 

We hope you enjoy this first batch…more is coming your way!

Don’t forget: You can listen to the full episode by clicking the link in the bio!❤️🙏🏾🧬 (1/7) https://t.co/mAH6YICuaK

Hey everybody! 👋🏾 As the show gears up for summer break, we would love to hear feedback from YOU - our audience! You can access our Season 2 Listener Survey by clicking the link below! (It’s completely anonymous too) 👍🏾❤️‍🔥 (1/2)

test Twitter Media - Hey everybody! 👋🏾 
As the show gears up for summer break, we would love to hear feedback from YOU - our audience! 
You can access our Season 2 Listener Survey by clicking the link below! (It’s completely anonymous too) 👍🏾❤️‍🔥 (1/2) https://t.co/LU6t7tSF7j

Podcast alert! “In Those Genes” is amazing if you’re into genetics, history, race and culture. Even if you aren’t it’s amazing and should be required listening. @inthosegenespod Retweeted by Dr. Jay Electronica

Medical gaslighting: Telling the patient that their problems will be solved with weight loss. REAL symptoms get brushed off. We know very little about optimal weight and health. Fatphobia is rooted in anti blackness: @inthosegenespod “Baby Got Black” @running2_med @lupusincolor Retweeted by Dr. Jay Electronica

Six years ago, I began investigating how genetics research gets appropriated and integrated into white supremacist ideologies. (1/n) Retweeted by Dr. Jay Electronica

Congrats to my big cousin @AMontgomery_998 Slate promotes Montgomery to VP of audio talkingbiznews.com/?p=124227

“Sometimes I’m afraid of my open mind”-oklama

Thank you @NYFRadioAwards and all our listeners from all of us here at In Those Genes! We couldn't have done this without y'all. 🎉

Congrats!!!! twitter.com/AMontgomery_99…

.@genome_gov and @NMAAHC are launching a four-part series that will underscore the advances made by African American people in biomedical and genetic research. Retweeted by Dr. Jay Electronica

The Jeff Lab Website

Curriculum Vitae