Past Crew Member: Janina M. Jeff, PhD, MS

Previous Positions

Crawford Graduate Student (2007-2012)

Crawford Post-Doctoral Fellow (2012-2013)

Post-Doctoral Fellow at the Icahn School of Medicine at Mount Sinai (2013-2015)

Current Position

Global Bioinformatics Specialist, Illumina (2015-present)

In Those Genes podcast, founder (2019-present) and ASHG Advocacy Awardee (2020)

Research Interests

As a genetic epidemiologist, Janina has an interest in identifying genetic variants that explain disease disparities observed across populations.  Janina has applied her interests to several common human diseases and traits including quantitative cardiovascular traits, anthropometric traits, hematological traits, reproductive outcomes, chronic kidney disease, type 2 diabetes, and pharmacogenomics in highly structured admixed populations such as African Americans and Hispanics.  Janina has developed approaches to extract data from a series of clinical data warehouses to define novel clinical phenotypes, for example extracting real-time physiologic response to short acting catacholamines administered during surgery for pharmacogenomic studies.

Recent Publications

  1. Wenric, S, Jeff, JM, Joseph, T, Yee, MC, Belbin, GM, Owusu Obeng, A, Ellis, SB, Bottinger, EP, Gottesman, O, Levin, MA et al.. Rapid response to the alpha-1 adrenergic agent phenylephrine in the perioperative period is impacted by genomics and ancestry. Pharmacogenomics J 2021; 21 (2): 174-189. PubMed PMID:33168928 PubMed Central PMC7997806.
  2. Pendergrass, SA, Buyske, S, Jeff, JM, Frase, A, Dudek, S, Bradford, Y, Ambite, JL, Avery, CL, Buzkova, P, Deelman, E et al.. A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans. PLoS One 2019; 14 (12): e0226771. PubMed PMID:31891604 PubMed Central PMC6938343.
  3. Edwards, TL, Giri, A, Hellwege, JN, Hartmann, KE, Stewart, EA, Jeff, JM, Bray, MJ, Pendergrass, SA, Torstenson, ES, Keaton, JM et al.. A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids. Front Genet 2019; 10 : 511. PubMed PMID:31249589 PubMed Central PMC6582231.
  4. Wojcik, GL, Graff, M, Nishimura, KK, Tao, R, Haessler, J, Gignoux, CR, Highland, HM, Patel, YM, Sorokin, EP, Avery, CL et al.. Genetic analyses of diverse populations improves discovery for complex traits. Nature 2019; 570 (7762): 514-518. PubMed PMID:31217584 PubMed Central PMC6785182.
  5. Fernández-Rhodes, L, Malinowski, JR, Wang, Y, Tao, R, Pankratz, N, Jeff, JM, Yoneyama, S, Carty, CL, Setiawan, VW, Le Marchand, L et al.. The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis. PLoS One 2018; 13 (7): e0200486. PubMed PMID:30044860 PubMed Central PMC6059436.
  6. Hellwege, JN, Jeff, JM, Wise, LA, Gallagher, CS, Wellons, M, Hartmann, KE, Jones, SF, Torstenson, ES, Dickinson, S, Ruiz-Narváez, EA et al.. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet 2017; 136 (11-12): 1497-1498. PubMed PMID:28975356 PubMed Central PMC5909202.
  7. Belbin, GM, Odgis, J, Sorokin, EP, Yee, MC, Kohli, S, Glicksberg, BS, Gignoux, CR, Wojcik, GL, Van Vleck, T, Jeff, JM et al.. Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system. Elife 2017; 6 : . PubMed PMID:28895531 PubMed Central PMC5595434.
  8. Hellwege, JN, Jeff, JM, Wise, LA, Gallagher, CS, Wellons, M, Hartmann, KE, Jones, SF, Torstenson, ES, Dickinson, S, Ruiz-Narváez, EA et al.. A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet 2017; 136 (10): 1363-1373. PubMed PMID:28836065 PubMed Central PMC5628188.
  9. Levin, MA, Joseph, TT, Jeff, JM, Nadukuru, R, Ellis, SB, Bottinger, EP, Kenny, EE. iGAS: A framework for using electronic intraoperative medical records for genomic discovery. J Biomed Inform 2017; 67 : 80-89. PubMed PMID:28193464 .
  10. Avery, CL, Wassel, CL, Richard, MA, Highland, HM, Bien, S, Zubair, N, Soliman, EZ, Fornage, M, Bielinski, SJ, Tao, R et al.. Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations. Heart Rhythm 2017; 14 (4): 572-580. PubMed PMID:27988371 PubMed Central PMC5448160.
Search PubMed

Janina on Twitter

By far one of the best interviews yet! Great way to open the season! twitter.com/blxckbones/sta…

We'll discuss “How The World Inherited Blackness” and how race (as conceptualized) impacts family history discovery journey with some of the @inthosegenespod team and guests from every episode! 🧬 🔗RSVP link in Bio. Tap in. 🧬 (4/4)

Race and “being Black” are not biological concepts. So how did “race” come to be this pervasive way we categorize humans? Why is it inextricably tied to the foundation of western science? And is there ANY biological basis for categorizing humans based on “race”? 🧬 (3/4)

@kinkofa is a comprehensive family history collective that is the future of genealogy through community research projects that honor & enhance the public’s understanding of African American contributions to history. 🧬 (2/4)

Nothing is better than likeminded folkx creating community! We are so pleased to announce that we are expanding our community with @kinkofa (KIN·koh·fah) for a new series, "In Our DNA" (shoutout to K dot!), a bi-weekly talk back for every episode in Season 2. 🧬 (1/4)

test Twitter Media - Nothing is better than likeminded folkx creating community! We are so pleased to announce that we are expanding our community with @kinkofa (KIN·koh·fah) for a new series, "In Our DNA" (shoutout to K dot!), a bi-weekly talk back for every episode in Season 2. 
🧬
(1/4) https://t.co/3NLQ0lcSFT

So hilarious @slamridd is a genius twitter.com/thee_body/stat…

@genome_gov "How The World Inherited Blackness"*

We are so humbled! If you haven't already join our virtual symposium that examines the history and present day manifestations of eugenics and scientific racism: go.usa.gov/xexQ7 hosted by @genome_gov today and tomorrow! Thanks @genome_gov twitter.com/genome_gov/sta…

Read our new post, "Championing a Diverse Genomics Workforce," a Q&A with Mr. Vence Bonham Jr., J.D., Acting Deputy Director of the @NIH’s @genome_gov, to find out how the Institute is cultivating diversity in genomics: go.usa.gov/xeyuR Retweeted by Dr. Jay Electronica

We love that we made your cut! twitter.com/NatalieBina2/s…

Our producers >>>>>> such a pleasure to work with such a talented crew twitter.com/danyabdelhamei…

i am *so excited* to announce our intent to publish the NIH Neuroscience Doctoral Readiness (DR) Program to to train and prepare a diverse pool of postbacs for PhD programs!! @NINDSDiversity @NIDAnews @NIDCR grants.nih.gov/grants/guide/n… Retweeted by Dr. Jay Electronica

@Black__Daria__ It’s one of the best parts of this season!!! Huge thanks to our HSIC (lol!) @slamridd who pulled out the A game in storytelling with @cin_pim @danyabdelhameid on the assists!!

Your favorite podcast is featured New Releases section in the @spotify app this morning! Have you listened to our first episode of Season 2?! If so tell us what you thought in the comments ⬇️

test Twitter Media - Your favorite podcast is featured New Releases section in the @spotify app this morning! Have you listened to our first episode of Season 2?! If so tell us what you thought in the comments ⬇️ https://t.co/F1xRxoiqnv

Yes it sets the stage for the goodness you serve us in the next two episodes! twitter.com/TinaLasisi/sta…

Excited for Season 2 of @inthosegenespod! Take a listen to Episode 1 which explores how race as we know it came to be and if it's genetic. Join us next week as we rap with Dr. Jeff about how race effects our family history discovery journey. twitter.com/inthosegenespo… Retweeted by Dr. Jay Electronica

If you’re into history, science, philosophy, & culture pulled together by 🔥 music, humor, skits, and immersive sound design — boy have we got a season in store for you. @inthosegenespod Szn 2 Ep 1 “How the World Inherited Blackness” now avail wherever you listen to pods twitter.com/inthosegenespo… Retweeted by Dr. Jay Electronica

Is Race Genetic? . Our first episode in Season 2 tells a story of “How the World Inherited Blackness” with experts @saigrundy and #DelandeJustinvil leading the field in sociology and anthropology. This story is filled with history, skits, and of course MUSIC!! 🎨by @dpicting

The Jeff Lab Website

Curriculum Vitae