PREP-aring is worth it: Success of the Case Western Reserve University Postbaccalaureate Research Education Program and its Scholars

Dana C. Crawford, Esteban Vazquez-Hidalgo, Hua Lou


The National Institute of General Medical Sciences (NIGMS) Postbaccalaureate Research Education Program (PREP)* was a research-intense, one-year training program for recent college graduates from experiential backgrounds uncommon in science who intended to matriculate with a PhD program in preparation for a career in biomedical research. Case Western Reserve University had an NIGMS-supported PREP (CasePREP) from 2007 until 2025, the year NIGMS terminated the program and early expired the PREP funding mechanism. We report here the extent that CasePREP, with its 108 Scholars, met program goals as well as the economic and scientific impact NIGMS-supported PREP has had for a variety of stakeholders. CasePREP was a great success as measured by its major outcomes: matriculation into a PhD or MD/PhD program (83%) and completion of degree (51 Scholars to date). CasePREP Scholars have persisted in science and have made substantial contributions to the scientific workforce and enterprise. PREPs in general provided a crucial bridge for research talents who had little prior research opportunities to realize their potential and career goals. NIGMS termination of PREP support has negative economic consequences and endangers an important pathway to a career in science for Americans who would not otherwise have similar opportunities.

*Hall A, Mann J, Bender M. Analysis of Scholar Outcomes for the NIGMS Postbaccalaureate Research Education Program (2015)

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Dana Crawford

Professor of Population and Quantitative Health Sciences and Associate Director of the Cleveland Institute for Computational Biology, with interest in pharmacogenomics, electronic health records, and diverse populations. Also, an avid foodie!