The American Society of Human Genetics annual meeting is one of the largest conferences for human genetics and genomics research. This year’s meeting will be held October 14-18, 2025 in Boston, Massachusetts. Like previous years, several CICB-affiliated scientists and their trainees will be presenting their cutting-edge research spanning many topics important in human diseases and traits.
From the Bush lab:
Multi-ancestry fine-mapping of causal variants in Alzheimer’s disease reveals extensive shared signals across ancestry groups, to be presented by Research Associate Penny Benchek, PhD
Local ancestry integration enhances interpretation of ASE in genetically diverse cohorts, to be presented by post-doctoral fellow Esteban Vazquez-Hidalgo, PhD
From cortex to cortex: decoding the shared genetic architecture between kidney function and Alzheimer’s disease, to be presented by Biomedical & Health Informatics (BHI) PhD candidate Diya Yang
Sparse vs dense modeling in multi-ancestry TWAS for Alzheimer’s disease, to be presented by BHI PhD candidate Xinyu Sun
Haptoglobin (HP) structural variants alter he effect of APOE alleles on Alzheimer’s disease in 5843 African-American individuals, to be presented by Systems Biology and Bioinformatics (SYBB) PhD candidate Yuchen Yang
African-ancestry meta-imputation improves genotype capture and accuracy of participants in the DAWN Alzheimer’s Research Study, to be presented by CICB faculty William Bush, PhD
From the Crawford lab:
Mapping functional variants in primary open-angle glaucoma through African continental genetic ancestry, to be presented by Epidemiology & Biostatistics (EPBI) PhD candidate Lauren Cruz
Major depressive disorder genetic risk scores in African Americans with postpartum depression, to be presented by EPBI PhD student Carly DaCosta
APOL1 renal risk variants, effect modifiers, and kidney function outcomes in the All of Us Research Program, to be presented by EPBI PhD alumna Shiying Liu, PhD
People living with genetic conditions and risk of late-onset Alzheimer diseases after COVID19 infection, to be presented by BHI PhD candidate Carly Rose
From the Haines lab:
eQTL fine-mapping analysis of variants within Alzheimer disease loci across ancestries in the Alzheimer Disease Genomics Consortium (ADGC), to be presented by post-doctoral fellow Michelle Grunin, PhD
Uncovering the genetic architecture of Alzheimer disease through pedigree-based heritability and rare variant analysis in the Midwestern Amish, to be presented by SYBB PhD candidate Yining Liu
Heritability of age-related macular degeneration in the Amish, to be presented by SYBB PhD candidate Noel Moore
Genome-wide association study of mosaic loss of chromosome Y in the Midwestern Amish, to be presented by Instructor Yeunjoo Song, PhD
From the Zhu lab:
Fine-mapping of overall and triple-negative breast cancer risk loci by integrating multiple tissue gene expression data, to be presented by BHI PhD candidate Mengxuan Li
Partitioning polygenic risk scores using tissue-restricted enhancers and their impacts on cardiovascular disease, to be presented by post-doctoral fellow Yihe Yang, PhD
Gene-gene interactions partially explain the association of FTO genotype with BMI variability, to be presented by Research Scientist Yajuan Wang, PhD
