Research shows that all COVID-19 infections include a wide mix of SARS-CoV-2 virus variants

September 8, 2022, 2pm Researchers at the Cleveland Institute for Computational Biology and Case Western Reserve University found wide genetic variation in SARS-CoV-2 viruses among 360 patients whose viral infections were genetically sequenced, showing that all individual infections include multiple variants of the virus. Led by the CICB’s Ricky Chan, researchers noted that reporting about […]

Dana Crawford, PhD, named an AAAS Fellow

Dana Crawford, PhD, has been named a fellow of the American Association for the Advancement of Science (AAAS). Crawford is a professor with the Department of Population and Quantitative Health Sciences and associate director of Population and Diversity Research with the Cleveland Institute of Computational Biology. The 2020 AAAS Fellows were formally announced in the […]

Satya Sahoo, PhD, Named a Fellow of AMIA

Satya Sahoo, PhD, has been named a Fellow of the American Medical Informatics Association. This achievement signals to colleagues and peers that the recipient is an expert in evidence-based informatics practice and engaged with a community that applies the latest advances in informatics to improve health and health care. Dr. Sahoo is an Associate Professor […]

Scott Williams, PhD, comments on predictive modeling

Scott Williams, PhD, recently commented to Cleveland.com on various COVID-19 prediction models, and why models can vary. Some of the variation involves the availability of timely data and confidence in the data, given how quickly things are changing. Read the full story here.

Combating Cancer: CWRU faculty highlight promising advances in diagnoses and treatments

Jill Barnholtz-Sloan, PhD, joined several faculty members for a CWRU THINK magazine feature highlighting the cancer research underway at Case Western Reserve University. Dr. Sloan’s focus is on using big data to better understand the mechanism of disease, its prevention, and treatment. “Having access to data from large sets of cancer patients beyond just your […]

Mind the Gap: Complications in returning data to study participants

People who participate in genetic research increasingly tell researchers that they want all of their genetic data back. But many of these participants do not have the data management infrastructure or analytical tools to interpret this information. And while third party companies eagerly offer to interpret results, they are unregulated and may offer incomplete or […]

Presentation: Returning genetic data: Farren Briggs, PhD, ScM

Farren Briggs, PhD ScM, recently presented on the challenges of returning genetic data to individual research participants. In his presentation, Dr. Briggs cautioned his colleagues about even making the most general of assumptions regarding their research participants, including their access to the internet and computing infrastructure, and their digital literacy. This is compounded by the […]

Jonathan Haines, PhD, and Will Bush, PhD, Part of International Collaboration that Makes Landmark Breakthroughs

An international study analyzing data from more than 94,000 people identified five new genes related to Alzheimer’s disease. The study also supports developing evidence that groups of genes associated with specific biological processes serve as genetic “hubs” that play an important role in the disease process. Funded in part by the National Institute on Aging […]

Chun Li, PhD, secures NIH grant on novel statistical methods

Chun Li, PhD, secures NIH grant to expand work on novel statistical methods In collaboration with Vanderbilt University Medical Center, CWRU researcher is developing techniques applied to the study of complex, chronic health conditions Cleveland, Ohio – A woman diagnosed with HIV works with her care team who consider many variables in tailoring a treatment […]