DANA C. CRAWFORD, PH.D.

Assistant Director for Population and Diversity Research

Dana Craw­ford, Ph.D., is Asso­ciate Pro­fes­sor in the Departments of Population and Quantitative Health Sciences (primary) and Genetics and Genome Sciences (secondary) and Assistant Director for Population and Diversity Research in the Insti­tute for Com­pu­ta­tional Biol­ogy. Dr. Craw­ford received her Ph.D. at Emory Uni­ver­sity in genet­ics and mol­e­c­u­lar biol­ogy in 2000 and then trained as a post-doctoral fel­low as an Epi­demic Intel­li­gence Ser­vice Offi­cer at the Cen­ters for Dis­ease Con­trol and Pre­ven­tion (2000–2002) and as a senior fel­low at the Uni­ver­sity of Washington’s Depart­ment of Genome Sci­ences (2002–2006). Prior to her most cur­rent posi­tion, Dr. Craw­ford spent eight years as tenure-track fac­ulty in Depart­ment of Mol­e­c­u­lar Phys­i­ol­ogy and Bio­physics and Inves­ti­ga­tor in the Cen­ter for Human Genet­ics Research at Van­der­bilt Uni­ver­sity. As a genetic epi­demi­ol­o­gist at CWRU, Dr. Crawford’s broad research inter­ests include apply­ing genetic vari­a­tion data to large-scale epi­demi­o­logic and clin­i­cal cohorts to bet­ter under­stand human genotype-phenotype asso­ci­a­tions with an empha­sis on diverse populations.

Affiliations

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Featured Publications

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project.

Crawford DC, Goodloe R, Brown-Gentry K, Wilson S, Roberson J, Gillani NB, Ritchie MD, Dilks HH, Bush WS,. Genome-wide association studies (GWAS) have identified hundreds of genomic regions associated with common human disease and quantitative traits. A major research avenue for mature genotype-phenotype associations is the identification of the true risk or functional variant for […]

Recent Publications

  1. Gong, J, Nishimura, KK, Fernandez-Rhodes, L, Haessler, J, Bien, S, Graff, M, Lim, U, Lu, Y, Gross, M, Fornage, M et al.. Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 2018; 42 (3): 384-390. PubMed PMID:29381148 PubMed Central PMC5876082.
  2. Bush, WS, Crawford, DC, Briggs, F, Freedman, D, Sloan, C. INTEGRATING COMMUNITY-LEVEL DATA RESOURCES FOR PRECISION MEDICINE RESEARCH. Pac Symp Biocomput 2018; 23 : 618-622. PubMed PMID:29218920 .
  3. Fish, AE, Crawford, DC, Capra, JA, Bush, WS. Local ancestry transitions modify snp-trait associations. Pac Symp Biocomput 2018; 23 : 424-435. PubMed PMID:29218902 PubMed Central PMC5728664.
  4. Conti, DV, Wang, K, Sheng, X, Bensen, JT, Hazelett, DJ, Cook, MB, Ingles, SA, Kittles, RA, Strom, SS, Rybicki, BA et al.. Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry. J. Natl. Cancer Inst. 2017; 109 (8): . PubMed PMID:29117387 PubMed Central PMC5448553.
  5. Goodloe, R, Farber-Eger, E, Boston, J, Crawford, DC, Bush, WS. Reducing Clinical Noise for Body Mass Index Measures Due to Unit and Transcription Errors in the Electronic Health Record. AMIA Jt Summits Transl Sci Proc 2017; 2017 : 102-111. PubMed PMID:28815116 PubMed Central PMC5543370.
  6. Farber-Eger, E, Goodloe, R, Boston, J, Bush, WS, Crawford, DC. Extracting Country-of-Origin from Electronic Health Records for Gene- Environment Studies as Part of the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) Study. AMIA Jt Summits Transl Sci Proc 2017; 2017 : 50-57. PubMed PMID:28815105 PubMed Central PMC5543359.
  7. Jones, CC, Bush, WS, Crawford, DC, Wenzlaff, AS, Schwartz, AG, Wiencke, JK, Wrensch, MR, Blot, WJ, Chanock, SJ, Grogan, EL et al.. Germline Genetic Variants and Lung Cancer Survival in African Americans. Cancer Epidemiol. Biomarkers Prev. 2017; 26 (8): 1288-1295. PubMed PMID:28619829 PubMed Central PMC5540773.
  8. Zubair, N, Graff, M, Luis Ambite, J, Bush, WS, Kichaev, G, Lu, Y, Manichaikul, A, Sheu, WH, Absher, D, Assimes, TL et al.. Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. Hum. Mol. Genet. 2016; 25 (24): 5500-5512. PubMed PMID:28426890 PubMed Central PMC5721937.
  9. Fernández-Rhodes, L, Gong, J, Haessler, J, Franceschini, N, Graff, M, Nishimura, KK, Wang, Y, Highland, HM, Yoneyama, S, Bush, WS et al.. Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci. Hum. Genet. 2017; 136 (6): 771-800. PubMed PMID:28391526 PubMed Central PMC5485655.
  10. Dumitrescu, L, Ritchie, MD, Denny, JC, El Rouby, NM, McDonough, CW, Bradford, Y, Ramirez, AH, Bielinski, SJ, Basford, MA, Chai, HS et al.. Genome-wide study of resistant hypertension identified from electronic health records. PLoS ONE 2017; 12 (2): e0171745. PubMed PMID:28222112 PubMed Central PMC5319785.
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