DANA C. CRAWFORD, PHD

Associate Director for Population and Diversity Research

Dana Craw­ford, PhD, is Pro­fes­sor in the Department of Population and Quantitative Health Sciences and Associate Director for Population and Diversity Research in the Cleveland Insti­tute for Com­pu­ta­tional Biol­ogy. She also has a secondary appointment in the Department of Genetics and Genome Sciences. Dr. Craw­ford received her Ph.D. at Emory Uni­ver­sity in genet­ics and mol­e­c­u­lar biol­ogy in 2000 and then trained as a post-doctoral fel­low as an Epi­demic Intel­li­gence Ser­vice Offi­cer at the Cen­ters for Dis­ease Con­trol and Pre­ven­tion (2000–2002) and as a senior fel­low at the Uni­ver­sity of Washington’s Depart­ment of Genome Sci­ences (2002–2006). Prior to her most cur­rent posi­tion, Dr. Craw­ford spent eight years as tenure-track fac­ulty in the Depart­ment of Mol­e­c­u­lar Phys­i­ol­ogy and Bio­physics and Inves­ti­ga­tor in the Cen­ter for Human Genet­ics Research at Van­der­bilt Uni­ver­sity. As a genetic epi­demi­ol­o­gist at CWRU, Dr. Crawford’s broad research inter­ests include apply­ing genetic vari­a­tion data to large-scale epi­demi­o­logic and clin­i­cal cohorts to bet­ter under­stand human genotype-phenotype asso­ci­a­tions with an empha­sis on diverse populations.

Recent Publications

  1. Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A, Schumacher, FR, Olama, AAA, Benlloch, S, Dadaev, T et al.. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 2021; 53 (3): 413. PubMed PMID:33473200 .
  2. Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A, Schumacher, FR, Olama, AAA, Benlloch, S, Dadaev, T et al.. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 2021; 53 (1): 65-75. PubMed PMID:33398198 .
  3. Cooke Bailey, JN, Bush, WS, Crawford, DC. Editorial: The Importance of Diversity in Precision Medicine Research. Front Genet 2020; 11 : 875. PubMed PMID:33005167 PubMed Central PMC7479241.
  4. Ong, E, Wang, LL, Schaub, J, O'Toole, JF, Steck, B, Rosenberg, AZ, Dowd, F, Hansen, J, Barisoni, L, Jain, S et al.. Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. Nat Rev Nephrol 2020; 16 (11): 686-696. PubMed PMID:32939051 PubMed Central PMC8012202.
  5. Karunamuni, RA, Huynh-Le, MP, Fan, CC, Thompson, W, Eeles, RA, Kote-Jarai, Z, Muir, K, UKGPCS Collaborators, Lophatananon, A, Tangen, CM et al.. African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. Int J Cancer 2021; 148 (1): 99-105. PubMed PMID:32930425 .
  6. McDonough, CW, Babcock, K, Chucri, K, Crawford, DC, Bian, J, Modave, F, Cooper-DeHoff, RM, Hogan, WR. Optimizing identification of resistant hypertension: Computable phenotype development and validation. Pharmacoepidemiol Drug Saf 2020; 29 (11): 1393-1401. PubMed PMID:32844549 PubMed Central PMC7754782.
  7. Darst, BF, Wan, P, Sheng, X, Bensen, JT, Ingles, SA, Rybicki, BA, Nemesure, B, John, EM, Fowke, JH, Stevens, VL et al.. A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. Eur Urol 2020; 78 (3): 316-320. PubMed PMID:32409115 PubMed Central PMC7805560.
  8. Pendergrass, SA, Buyske, S, Jeff, JM, Frase, A, Dudek, S, Bradford, Y, Ambite, JL, Avery, CL, Buzkova, P, Deelman, E et al.. A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans. PLoS One 2019; 14 (12): e0226771. PubMed PMID:31891604 PubMed Central PMC6938343.
  9. Crawford, DC, Lin, J, Cooke Bailey, JN, Kinzy, T, Sedor, JR, O'Toole, JF, Bush, WS. Frequency of ClinVar Pathogenic Variants in Chronic Kidney Disease Patients Surveyed for Return of Research Results at a Cleveland Public Hospital. Pac Symp Biocomput 2020; 25 : 575-586. PubMed PMID:31797629 PubMed Central PMC6931908.
  10. Bush, WS, Cooke Bailey, JN, Beno, MF, Crawford, DC. Bridging the Gaps in Personalized Medicine Value Assessment: A Review of the Need for Outcome Metrics across Stakeholders and Scientific Disciplines. Public Health Genomics 2019; 22 (1-2): 16-24. PubMed PMID:31454805 PubMed Central PMC6752968.
Search PubMed

Featured Publications

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project.

Crawford DC, Goodloe R, Brown-Gentry K, Wilson S, Roberson J, Gillani NB, Ritchie MD, Dilks HH, Bush WS,. Genome-wide association studies (GWAS) have identified hundreds of genomic regions associated with common human disease and quantitative traits. A major research avenue for mature genotype-phenotype associations is the identification of the true risk or functional variant for […]

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.

Bush WS, Boston J, Pendergrass SA, Dumitrescu L, Goodloe R, Brown-Gentry K, Wilson S, McClellan B, Torstenson E, Basford MA, Spencer KL, Ritchie MD, Crawford DC,. Genetic association studies have rapidly become a major tool for identifying the genetic basis of common human diseases. The advent of cost-effective genotyping coupled with large collections of samples […]

Dana on Twitter

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Dr. Dana Crawford 2 weeks ago

For sale: #ketchup packets, ready use. #ketchupshortage

test Twitter Media - For sale: #ketchup packets, ready use. #ketchupshortage https://t.co/TbCRoua96k
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Dr. Dana Crawford 2 weeks ago

Have family, friends, or even colleagues spouting misinformation about COVID-19 vaccines? Here's a webinar for you! #COVID19Vaccine #COVID19 twitter.com/GeneticsSociet…

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Dr. Dana Crawford 2 weeks ago

Srsly? twitter.com/NHGRI_Director…

test Twitter Media - Srsly? https://t.co/HqDZEOJNLY https://t.co/zSpbShoirU
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Dr. Dana Crawford 3 weeks ago

Need a reason to nominate your colleague for an @ASHG 2021 award? Check out how it's going for @inthosegenepod Dr Janina Jeff, 2020 ASHG Advocacy Award winner! Six #ASHG21 awards are waiting for your nominations, due April 22nd... bit.ly/3rC8gYu twitter.com/inthosegenespo…

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Dr. Dana Crawford 3 weeks ago

Redfield and others like him use the weight of science and leadership positions to amplify conspiracy theories without actual scientific evidence, all under the cowardly protection of "opinions are my own." #notarealscientist twitter.com/CUEpidemiology…

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ASHG 4 weeks ago

ASHG is deeply troubled by recent acts of violence against the Asian American community. We condemn these acts of hatred, as well as all acts of racism, bias and discrimination. Read the full statement by ASHG President Gail Jarvik, MD, PhD on our website: bit.ly/31kjsgR Retweeted by Dr. Dana Crawford

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Dr. Dana Crawford 1 month ago

A few ideas for your 15 minutes. youtu.be/BWWzmha1_jE #yoyoma #COVID19Vaccine twitter.com/Caroline_Bartm…

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Dr. Dana Crawford 1 month ago

Wow: @crystaljjlee of @mitvis show in beautiful and informative data visualizations that @GovMikeDeWine is frequently mentioned in the anti-masker social networks. Hits too close to home in more than one way. #WearAMask twitter.com/mitvis/status/…

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Dr. Dana Crawford 1 month ago

"That is very frustrating from a scientific standpoint and becomes extremely problematic when you're trying to implement a public health effort that could be lifesaving," he says. "And when you don't implement it, well, people die. That's serious."--Dr. Fauci twitter.com/NPR/status/136…

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Dr. Dana Crawford 1 month ago

@MikeEberle It’s hard to say—they were both wearing masks. #WearAMask

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Dr. Dana Crawford 1 month ago

Received two compliments today at two separate businesses for my science mask combo. Gives me hope that people don’t believe all the garbage online about #COVID19. Let’s not be TX, OH. #WearAMask

test Twitter Media - Received two compliments today at two separate businesses for my science mask combo. Gives me hope that people don’t believe all the garbage online about #COVID19. Let’s not be TX, OH. #WearAMask https://t.co/ho4v8HBW9f
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Dr. Dana Crawford 2 months ago

@GreeneScientist @ontowonka @CUAnschutz WHAT? This is HUGE! Congrats to @GreeneScientist @ontowonka -- looks like you @CUAnschutz are building something great!

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Dr. Dana Crawford 2 months ago

Feeling a pang of nostalgia for our old Nashville home. So much respect for @DollyParton in her artistry, philanthropy, and enormous capacity for compassion. Such a responsible use of celebrity. Here's hoping for another song on the second dose. twitter.com/DollyParton/st…

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Dr. Dana Crawford 2 months ago

test Twitter Media - https://t.co/ZuxOeRREZx
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Dr. Dana Crawford 2 months ago

No pseudoscience here! Thrilled to have been invited by @clschuerger and @CWRU Women in Sciences and Humanities Earning Doctorates (WISHED) for last week's early evening discussion of big data and bias in research and in life.

test Twitter Media - No pseudoscience here! Thrilled to have been invited by @clschuerger and @CWRU Women in Sciences and Humanities Earning Doctorates (WISHED) for last week's early evening discussion of big data and bias in research and in life. https://t.co/ALStV9SeLd
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Dr. Dana Crawford 2 months ago

Putting real science to meaningful practice: @CWRU is now an official vaccination site for the Cleveland area. case.edu/vaccine/ #COVID19

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Dr. Dana Crawford 2 months ago

So proud to be associated with a scientist who applies her expertise and rigor in all her endeavors e.g., award winning "Dat Rona" episode dispelling harmful lies and conspiracy theories about COVID-19 severity and vaccines. #COVID19 tinyurl.com/czmzmza twitter.com/inthosegenespo…

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Muin J. Khoury 2 months ago

Genomics is an essential addition to the public health response to rare diseases. #RareDiseaseDay blogs.cdc.gov/genomics/2017/… Retweeted by Dr. Dana Crawford

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Dr. Jay Electronica 2 months ago

Meanwhile (unbeknownst to me) at @AstraZeneca I’m hanging on the Black History in Science wall next to the Vice President @kamalaharris 🧬🧬🧬. . Happy Black History Month✊🏽 Retweeted by Dr. Dana Crawford

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Dr. Dana Crawford 2 months ago

East Carolina University's @DrEricSoule is performing a survey of African American/Black scientists to better understand what barriers may exist in serving on NIH study sections. Check out hhp.ecu.edu/hep/hbtrl/ for more information on how to participate if you are interested.

Affiliations

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