DANA C. CRAWFORD, PHD

Associate Director for Population and Diversity Research

Dana Craw­ford, PhD, is Pro­fes­sor in the Department of Population and Quantitative Health Sciences and Associate Director for Population and Diversity Research in the Cleveland Insti­tute for Com­pu­ta­tional Biol­ogy. She also has a secondary appointment in the Department of Genetics and Genome Sciences. Dr. Craw­ford received her Ph.D. at Emory Uni­ver­sity in genet­ics and mol­e­c­u­lar biol­ogy in 2000 and then trained as a post-doctoral fel­low as an Epi­demic Intel­li­gence Ser­vice Offi­cer at the Cen­ters for Dis­ease Con­trol and Pre­ven­tion (2000–2002) and as a senior fel­low at the Uni­ver­sity of Washington’s Depart­ment of Genome Sci­ences (2002–2006). Prior to her most cur­rent posi­tion, Dr. Craw­ford spent eight years as tenure-track fac­ulty in the Depart­ment of Mol­e­c­u­lar Phys­i­ol­ogy and Bio­physics and Inves­ti­ga­tor in the Cen­ter for Human Genet­ics Research at Van­der­bilt Uni­ver­sity. As a genetic epi­demi­ol­o­gist at CWRU, Dr. Crawford’s broad research inter­ests include apply­ing genetic vari­a­tion data to large-scale epi­demi­o­logic and clin­i­cal cohorts to bet­ter under­stand human genotype-phenotype asso­ci­a­tions with an empha­sis on diverse populations.

Recent Publications

  1. Cooke Bailey, JN, Bush, WS, Crawford, DC. Editorial: The Importance of Diversity in Precision Medicine Research. Front Genet 2020; 11 : 875. PubMed PMID:33005167 PubMed Central PMC7479241.
  2. Ong, E, Wang, LL, Schaub, J, O'Toole, JF, Steck, B, Rosenberg, AZ, Dowd, F, Hansen, J, Barisoni, L, Jain, S et al.. Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. Nat Rev Nephrol 2020; 16 (11): 686-696. PubMed PMID:32939051 .
  3. Karunamuni, RA, Huynh-Le, MP, Fan, CC, Thompson, W, Eeles, RA, Kote-Jarai, Z, Muir, K, UKGPCS Collaborators, Lophatananon, A, Tangen, CM et al.. African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. Int J Cancer 2020; : . PubMed PMID:32930425 .
  4. McDonough, CW, Babcock, K, Chucri, K, Crawford, DC, Bian, J, Modave, F, Cooper-DeHoff, RM, Hogan, WR. Optimizing identification of resistant hypertension: Computable phenotype development and validation. Pharmacoepidemiol Drug Saf 2020; : . PubMed PMID:32844549 .
  5. Darst, BF, Wan, P, Sheng, X, Bensen, JT, Ingles, SA, Rybicki, BA, Nemesure, B, John, EM, Fowke, JH, Stevens, VL et al.. A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. Eur Urol 2020; 78 (3): 316-320. PubMed PMID:32409115 .
  6. Pendergrass, SA, Buyske, S, Jeff, JM, Frase, A, Dudek, S, Bradford, Y, Ambite, JL, Avery, CL, Buzkova, P, Deelman, E et al.. A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans. PLoS One 2019; 14 (12): e0226771. PubMed PMID:31891604 PubMed Central PMC6938343.
  7. Crawford, DC, Lin, J, Cooke Bailey, JN, Kinzy, T, Sedor, JR, O'Toole, JF, Bush, WS. Frequency of ClinVar Pathogenic Variants in Chronic Kidney Disease Patients Surveyed for Return of Research Results at a Cleveland Public Hospital. Pac Symp Biocomput 2020; 25 : 575-586. PubMed PMID:31797629 PubMed Central PMC6931908.
  8. Bush, WS, Cooke Bailey, JN, Beno, MF, Crawford, DC. Bridging the Gaps in Personalized Medicine Value Assessment: A Review of the Need for Outcome Metrics across Stakeholders and Scientific Disciplines. Public Health Genomics 2019; 22 (1-2): 16-24. PubMed PMID:31454805 PubMed Central PMC6752968.
  9. Halladay, CW, Hadi, T, Anger, MD, Greenberg, PB, Sullivan, JM, Konicki, PE, Peachey, NS, Igo, RP Jr, Iyengar, SK, Wu, WC et al.. Genetically-guided algorithm development and sample size optimization for age-related macular degeneration cases and controls in electronic health records from the VA Million Veteran Program. AMIA Jt Summits Transl Sci Proc 2019; 2019 : 153-162. PubMed PMID:31258967 PubMed Central PMC6568141.
  10. Crawford, DC, Cooke Bailey, JN, Briggs, FBS. Mind the gap: resources required to receive, process and interpret research-returned whole genome data. Hum Genet 2019; 138 (7): 691-701. PubMed PMID:31161416 PubMed Central PMC6767905.
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Featured Publications

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project.

Crawford DC, Goodloe R, Brown-Gentry K, Wilson S, Roberson J, Gillani NB, Ritchie MD, Dilks HH, Bush WS,. Genome-wide association studies (GWAS) have identified hundreds of genomic regions associated with common human disease and quantitative traits. A major research avenue for mature genotype-phenotype associations is the identification of the true risk or functional variant for […]

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.

Bush WS, Boston J, Pendergrass SA, Dumitrescu L, Goodloe R, Brown-Gentry K, Wilson S, McClellan B, Torstenson E, Basford MA, Spencer KL, Ritchie MD, Crawford DC,. Genetic association studies have rapidly become a major tool for identifying the genetic basis of common human diseases. The advent of cost-effective genotyping coupled with large collections of samples […]

Dana on Twitter

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Dana Crawford 4 days ago

Thanks to everyone at #SACNAS2020 who came to our Precisely Precision Medicine session today! If you want to chat with us @Cleveland_ICB , reach out on the platform during the conference or contact us at tinyurl.com/y6xzquss

test Twitter Media - Thanks to everyone at #SACNAS2020 who came to our Precisely Precision Medicine session today! If you want to chat with us @Cleveland_ICB , reach out on the platform during the conference or contact us at https://t.co/DxVGW9pD0t https://t.co/8y28SxeP89
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Dana Crawford 4 days ago

@Cleveland_ICB twitter.com/CaturDNA/statu…

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Dana Crawford 4 days ago

Don’t miss our #SACNAS2020 Precisely Precision Medicine presentation today! It’s got electronic health records, genomics, return of research results, and bioethics! What more could you want? @icompbio

test Twitter Media - Don’t miss our #SACNAS2020 Precisely Precision Medicine presentation today! It’s got electronic health records, genomics, return of research results, and bioethics! What more could you want? @icompbio https://t.co/oDzj8BK2my
test Twitter Media - Don’t miss our #SACNAS2020 Precisely Precision Medicine presentation today! It’s got electronic health records, genomics, return of research results, and bioethics! What more could you want? @icompbio https://t.co/oDzj8BK2my
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Dana Crawford 6 days ago

Adding to the photo gallery at #SACNAS2020!

test Twitter Media - Adding to the photo gallery at #SACNAS2020! https://t.co/jGvLkCh9HF
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Dana Crawford 6 days ago

The videos are out! Congrats to @inthosegenespod for your Advocacy Award from ASHG @GeneticsSociety #ASHG2020 pathlms.com/ashg/courses/2…

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Dana Crawford 1 week ago

Your aloha Friday: The 2021 Pacific Symposium on Biocomputing (PSB) proceedings are out! psb.stanford.edu #psb21

test Twitter Media - Your aloha Friday: The 2021 Pacific Symposium on Biocomputing (PSB) proceedings are out! https://t.co/OuQq1sxG1q #psb21 https://t.co/cUW5nI0Lap
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Innovative Genomics Institute 2 weeks ago

How it started: How it's going: Retweeted by Dana Crawford

test Twitter Media - RT @igisci: How it started: How it's going: https://t.co/mlLzxNug5q
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Dana Crawford 2 weeks ago

@SetiaShefali @biomonika @mbyrskabishop @AniaOkulaBasile @pyromanticism @marieguerraty @RachelKember @__yoson__ @VujkovicM @Madhuvika @RenaeJudy Amplify 10 women in science #WomenInScience #ScienceTwitter @MGrunin5 @ellelnutter @shiying_l @MelanieMyers_ @K_Actkins @ARWaksmunski @a_k_miller @XueyiZhang_J @blancahimes @CruzLauren_

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Dana Crawford 3 weeks ago

Maybe he can ask @FullFrontalSamB if his campaign can borrow Herman Cain's old campaign wheels. twitter.com/colbertlatesho…

test Twitter Media - Maybe he can ask @FullFrontalSamB if his campaign can borrow Herman Cain's old campaign wheels. https://t.co/fOwmIfiua9 https://t.co/ZCxiqet3Qp
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Dana Crawford 3 weeks ago

Great. And they were just here in Cleveland around our campus. I'll be watching @NextStrain for signs of any sequences that can be traced back to #Debates2020.

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Dana Crawford 4 weeks ago

@cwru @jimmykimmel @gmail @Russo_Brothers Hey @jimmykimmel--@iamsambee with @FullFrontalSamB danced on our #CWRU campus back in 2016. Recognize it now?

test Twitter Media - @cwru @jimmykimmel @gmail @Russo_Brothers Hey @jimmykimmel--@iamsambee with @FullFrontalSamB danced on our #CWRU campus back in 2016. Recognize it now? https://t.co/UbEzZBHX3A
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Case Western Reserve 1 month ago

Hey @JimmyKimmel! You may not have heard of us, but we'd love to share more about #CWRU with you. From the inventor of @gmail to the @Russo_brothers, we're pretty sure you're familiar with our alumni's work! Visit case.edu/about to learn more. Retweeted by Dana Crawford

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Caitrin McDonough 1 month ago

I am recruiting for a postdoc position focused on PGx research and EHR data science at @UFPharmacy. PhD or PharmD trained. Posting isn’t live yet. If interested- contact me for more info (link w/email in bio). Pls RT. #postdoc #pgx #ehr Retweeted by Dana Crawford

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Patton Oswalt 1 month ago

Mandy has “The” Sword! #PrincessBrideReunion Retweeted by Dana Crawford

test Twitter Media - RT @pattonoswalt: Mandy has “The” Sword! #PrincessBrideReunion https://t.co/FphXnXdskV
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Dana Crawford 1 month ago

Josh Gad—you’re on mute!

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Dana Crawford 1 month ago

#PrincessBrideReunion !!!

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Julia Austin 2 months ago

"I've known a great many clever men. I've outlived them all. You know why? I ignored them. The lords of Westeros are sheep. Are you a sheep? No. You're a dragon. Be a dragon." Best line from GoT. RIP Dame Diana Rigg 💙 twitter.com/i/events/13040… Retweeted by Dana Crawford

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Dana Crawford 2 months ago

Congrats to @CWRUSOM's @a_k_miller, @scottwilliams9, and @BuchnerLab for being selected for a platform presentation at the upcoming #ASHG2020! Looking forward to the epistasis talk at 10:45am ET on 10/28 (abstract 1124).

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Dana Crawford 2 months ago

Missed the @Cleveland_ICB North Coast Conference on Precision Medicine? Don't worry-- recorded talks by @K_Actkins, @a_k_miller, @li_ruowang, Carla Márquez Luna, Fred Schumacher, Jessica Cooke Bailey, and Athena Starlard-Davenport are all available at tinyurl.com/y4u35rbw

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Dana Crawford 2 months ago

Thanks for the shoutout @wakibbe! For those interested in this topic, please consider contributing your work to a new call for papers co-organized by @genome_gov NHGRI's Dr. Lucia Hindorff: tinyurl.com/y69qwcz9 twitter.com/wakibbe/status…

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