DANA C. CRAWFORD, PHD

Associate Director for Population and Diversity Research

Dana Craw­ford, PhD, is Pro­fes­sor in the Department of Population and Quantitative Health Sciences and Associate Director for Population and Diversity Research in the Cleveland Insti­tute for Com­pu­ta­tional Biol­ogy. She also has a secondary appointment in the Department of Genetics and Genome Sciences. Dr. Craw­ford received her Ph.D. at Emory Uni­ver­sity in genet­ics and mol­e­c­u­lar biol­ogy in 2000 and then trained as a post-doctoral fel­low as an Epi­demic Intel­li­gence Ser­vice Offi­cer at the Cen­ters for Dis­ease Con­trol and Pre­ven­tion (2000–2002) and as a senior fel­low at the Uni­ver­sity of Washington’s Depart­ment of Genome Sci­ences (2002–2006). Prior to her most cur­rent posi­tion, Dr. Craw­ford spent eight years as tenure-track fac­ulty in the Depart­ment of Mol­e­c­u­lar Phys­i­ol­ogy and Bio­physics and Inves­ti­ga­tor in the Cen­ter for Human Genet­ics Research at Van­der­bilt Uni­ver­sity. As a genetic epi­demi­ol­o­gist at CWRU, Dr. Crawford’s broad research inter­ests include apply­ing genetic vari­a­tion data to large-scale epi­demi­o­logic and clin­i­cal cohorts to bet­ter under­stand human genotype-phenotype asso­ci­a­tions with an empha­sis on diverse populations.

Recent Publications

  1. Crawford, DC, Williams, SM. Global variation in sequencing impedes SARS-CoV-2 surveillance. PLoS Genet 2021; 17 (7): e1009620. PubMed PMID:34264957 PubMed Central PMC8282079.
  2. Crawford, DC, Sedor, JR. Biobanks Linked to Electronic Health Records Accelerate Genomic Discovery. J Am Soc Nephrol 2021; 32 (8): 1828-1829. PubMed PMID:34244324 .
  3. Karunamuni, RA, Huynh-Le, MP, Fan, CC, Thompson, W, Lui, A, Martinez, ME, Rose, BS, Mahal, B, Eeles, RA, Kote-Jarai, Z et al.. Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24. Prostate Cancer Prostatic Dis 2021; : . PubMed PMID:34127801 .
  4. Schmidt, IM, Colona, MR, Kestenbaum, BR, Alexopoulos, LG, Palsson, R, Srivastava, A, Liu, J, Stillman, IE, Rennke, HG, Vaidya, VS et al.. Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis. Kidney Int 2021; 100 (3): 672-683. PubMed PMID:34051265 PubMed Central PMC8384690.
  5. Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A, Schumacher, FR, Olama, AAA, Benlloch, S, Dadaev, T et al.. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 2021; 53 (3): 413. PubMed PMID:33473200 .
  6. Conti, DV, Darst, BF, Moss, LC, Saunders, EJ, Sheng, X, Chou, A, Schumacher, FR, Olama, AAA, Benlloch, S, Dadaev, T et al.. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 2021; 53 (1): 65-75. PubMed PMID:33398198 PubMed Central PMC8148035.
  7. Cooke Bailey, JN, Bush, WS, Crawford, DC. Editorial: The Importance of Diversity in Precision Medicine Research. Front Genet 2020; 11 : 875. PubMed PMID:33005167 PubMed Central PMC7479241.
  8. Ong, E, Wang, LL, Schaub, J, O'Toole, JF, Steck, B, Rosenberg, AZ, Dowd, F, Hansen, J, Barisoni, L, Jain, S et al.. Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. Nat Rev Nephrol 2020; 16 (11): 686-696. PubMed PMID:32939051 PubMed Central PMC8012202.
  9. Karunamuni, RA, Huynh-Le, MP, Fan, CC, Thompson, W, Eeles, RA, Kote-Jarai, Z, Muir, K, UKGPCS Collaborators, Lophatananon, A, Tangen, CM et al.. African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. Int J Cancer 2021; 148 (1): 99-105. PubMed PMID:32930425 PubMed Central PMC8135907.
  10. McDonough, CW, Babcock, K, Chucri, K, Crawford, DC, Bian, J, Modave, F, Cooper-DeHoff, RM, Hogan, WR. Optimizing identification of resistant hypertension: Computable phenotype development and validation. Pharmacoepidemiol Drug Saf 2020; 29 (11): 1393-1401. PubMed PMID:32844549 PubMed Central PMC7754782.
Search PubMed

Featured Publications

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project.

Crawford DC, Goodloe R, Brown-Gentry K, Wilson S, Roberson J, Gillani NB, Ritchie MD, Dilks HH, Bush WS,. Genome-wide association studies (GWAS) have identified hundreds of genomic regions associated with common human disease and quantitative traits. A major research avenue for mature genotype-phenotype associations is the identification of the true risk or functional variant for […]

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.

Bush WS, Boston J, Pendergrass SA, Dumitrescu L, Goodloe R, Brown-Gentry K, Wilson S, McClellan B, Torstenson E, Basford MA, Spencer KL, Ritchie MD, Crawford DC,. Genetic association studies have rapidly become a major tool for identifying the genetic basis of common human diseases. The advent of cost-effective genotyping coupled with large collections of samples […]

Dana on Twitter

ATTN early-career scientists from diverse backgrounds: Engage in conversations at the forefront of biology with academic, industry and government thought-leaders from around the world! Apply to keystonesymposia.org/Fellows #KSFellows #MentorshipMatters Retweeted by Dr. Dana Crawford

Squirrels doing parkour! Happy Science Friday! twitter.com/evolambert/sta…

If you want to spend January 2022 here (Fairmont Orchid Big Island), submit a paper to @PacSymBiocomp by August 2! Our session is "Precision Medicine: Using Artificial Intelligence to improve diagnostics and healthcare"! psb.stanford.edu/callfor/papers… Retweeted by Dr. Dana Crawford

4/n: I am a COVID vaccine inventor. … In Louisiana… a “hot-spot”… watching the virus do what viruses do. … Feeling helpless because people are opting out of the vaccine. I um… I… I don’t have the words. Retweeted by Dr. Dana Crawford

Inadequate sequencing of SARS-CoV-2 variants impedes global response to COVID-19 medicalxpress.com/news/2021-07-i… via @medical_xpress Retweeted by Dr. Dana Crawford

#PLOSGenetics: Global variation in sequencing impedes SARS-CoV-2 surveillance dx.plos.org/10.1371/journa… With resurgence knowing accumulation and distribution of new variants is even more critical Retweeted by Dr. Dana Crawford

#PSB22 Aloha! The Call for Papers deadline is on August 2; see psb.stanford.edu/callfor/papers/. Hope to see you on the Big Island! Retweeted by Dr. Dana Crawford

>70% of @CWRU's graduate and professional students have been vaccinated! Many thanks to each and every one of you for keeping those who can't get vaccinated safe! #CovidVaccine #COVID19Vaccine

I was shocked to hear of his passing earlier this month. He was on my dissertation committee and was a key mentor and collaborator in my graduate work on Fragile X. What a loss to the field, family, and friends. twitter.com/EmoryGenetics/…

Want to spend January 2022 on the Big Island of Hawaii? Submit to @PacSymBiocomp session Precision Medicine: Using Artificial Intelligence to improve diagnostics and healthcare! @CaturDNA @jonc101x @IAmSamFin @kidzik psb.stanford.edu/callfor/papers… Retweeted by Dr. Dana Crawford

Always a joy to be reminded that some colleagues place more value on the title rather than the actual work. #AcademicChatter

Heard from a dental 🦷 colleague during a meeting: "We were doing PPE before it was cool." #AcademicChatter

@AniaOkulaBasile @MarylynRitchie @_jjdubs @nicktatonetti @_anuragverma @vumcdbmi @CPMGatColumbia @PennMedicine @AniaOkulaBasile I am so going to use parts of this figure for talks. Loving the diversity depicted in the figure, BTW.

CWRU postdoctoral @ARWaksmunski is in my inbox reminding me to get my @GeneticsSociety abstract ready for #ASHG21!

test Twitter Media - CWRU postdoctoral @ARWaksmunski is in my inbox reminding me to get my @GeneticsSociety abstract ready for #ASHG21! https://t.co/kE7hqB4nuR

Happy #DNADay2021! Today commemorates the successful completion of the Human Genome Project in 2003 and the discovery of DNA’s double helix in 1953, and celebrates past and future accomplishments in human genetics research. Retweeted by Dr. Dana Crawford

Love me some #TedLasso! twitter.com/AppleTV/status…

test Twitter Media - Love me some #TedLasso! https://t.co/amWKKdDIis https://t.co/vyc3n6gvEP

Thank you @RepJeffDuncan for supporting GGC's genetic services and research here in SC - and to those who are sharing the impact of genetic research during @GeneticsSociety's #Hillday twitter.com/GeneticsSociet… Retweeted by Dr. Dana Crawford

We have successfully concluded ASHG's first ever virtual #HillDay. Thank you to everyone who made their voices heard through social media and in congressional meetings. We also thank the Hill staff offices for taking the time to speak with us throughout the day. #FundNIH Retweeted by Dr. Dana Crawford

Affiliations

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Curriculum vitae