DANA C. CRAWFORD, PHD

Associate Director for Population and Diversity Research

Dana Craw­ford, PhD, is Pro­fes­sor in the Department of Population and Quantitative Health Sciences and Associate Director for Population and Diversity Research in the Cleveland Insti­tute for Com­pu­ta­tional Biol­ogy. She also has a secondary appointment in the Department of Genetics and Genome Sciences. Dr. Craw­ford received her Ph.D. at Emory Uni­ver­sity in genet­ics and mol­e­c­u­lar biol­ogy in 2000 and then trained as a post-doctoral fel­low as an Epi­demic Intel­li­gence Ser­vice Offi­cer at the Cen­ters for Dis­ease Con­trol and Pre­ven­tion (2000–2002) and as a senior fel­low at the Uni­ver­sity of Washington’s Depart­ment of Genome Sci­ences (2002–2006). Prior to her most cur­rent posi­tion, Dr. Craw­ford spent eight years as tenure-track fac­ulty in the Depart­ment of Mol­e­c­u­lar Phys­i­ol­ogy and Bio­physics and Inves­ti­ga­tor in the Cen­ter for Human Genet­ics Research at Van­der­bilt Uni­ver­sity. As a genetic epi­demi­ol­o­gist at CWRU, Dr. Crawford’s broad research inter­ests include apply­ing genetic vari­a­tion data to large-scale epi­demi­o­logic and clin­i­cal cohorts to bet­ter under­stand human genotype-phenotype asso­ci­a­tions with an empha­sis on diverse populations.

Recent Publications

  1. Liu, J, Nair, V, Zhao, YY, Chang, DY, Limonte, C, Bansal, N, Fermin, D, Eichinger, F, Tanner, EC, Bellovich, KA et al.. Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease. Diabetes 2022; 71 (12): 2664-2676. PubMed PMID:36331122 .
  2. Yang, HT, Crawford, DC, Abazeed, ME. Editorial: Translating clinical genomics and health informatics into precision oncology. Front Genet 2022; 13 : 1029212. PubMed PMID:36263433 PubMed Central PMC9574329.
  3. Lutnick, B, Manthey, D, Becker, JU, Ginley, B, Moos, K, Zuckerman, JE, Rodrigues, L, Gallan, AJ, Barisoni, L, Alpers, CE et al.. A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology. Commun Med (Lond) 2022; 2 : 105. PubMed PMID:35996627 PubMed Central PMC9391340.
  4. Liu, S, Bush, WS, Miskimen, K, Gonzalez-Vicente, A, Bailey, JNC, Konidari, I, McCauley, JL, Sedor, JR, O'Toole, JF, Crawford, DC et al.. T-cell receptor diversity in minimal change disease in the NEPTUNE study. Pediatr Nephrol 2022; : . PubMed PMID:35943576 .
  5. Waksmunski, AR, Kinzy, TG, Cruz, LA, Nealon, CL, Halladay, CW, Simpson, P, Canania, RL, Anthony, SA, Roncone, DP, Sawicki Rogers, L et al.. Glaucoma Genetic Risk Scores in the Million Veteran Program. Ophthalmology 2022; 129 (11): 1263-1274. PubMed PMID:35718050 .
  6. Verma, A, Tsao, NL, Thomann, LO, Ho, YL, Iyengar, SK, Luoh, SW, Carr, R, Crawford, DC, Efird, JT, Huffman, JE et al.. A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program. PLoS Genet 2022; 18 (4): e1010113. PubMed PMID:35482673 PubMed Central PMC9049369.
  7. Menon, R, Bomback, AS, Lake, BB, Stutzke, C, Grewenow, SM, Menez, S, D'Agati, VD, Jain, S, Kidney Precision Medicine Project. Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation. Kidney Int 2022; 101 (6): 1116-1125. PubMed PMID:35339536 .
  8. Peloso, GM, Tcheandjieu, C, McGeary, JE, Posner, DC, Ho, YL, Zhou, JJ, Hilliard, AT, Joseph, J, O'Donnell, CJ, Efird, JT et al.. Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program. Front Genet 2021; 12 : 777076. PubMed PMID:35222515 PubMed Central PMC8864634.
  9. Jin, B, Capra, JA, Benchek, P, Wheeler, N, Naj, AC, Hamilton-Nelson, KL, Farrell, JJ, Leung, YY, Kunkle, B, Vadarajan, B et al.. An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns. Genome Res 2022; 32 (4): 778-790. PubMed PMID:35210353 PubMed Central PMC8997344.
  10. Huynh-Le, MP, Karunamuni, R, Fan, CC, Asona, L, Thompson, WK, Martinez, ME, Eeles, RA, Kote-Jarai, Z, Muir, KR, Lophatananon, A et al.. Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score. Prostate Cancer Prostatic Dis 2022; 25 (4): 755-761. PubMed PMID:35152271 PubMed Central PMC9372232.
Search PubMed

Featured Publications

Characterization of the Metabochip in diverse populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project.

Crawford DC, Goodloe R, Brown-Gentry K, Wilson S, Roberson J, Gillani NB, Ritchie MD, Dilks HH, Bush WS,. Genome-wide association studies (GWAS) have identified hundreds of genomic regions associated with common human disease and quantitative traits. A major research avenue for mature genotype-phenotype associations is the identification of the true risk or functional variant for […]

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.

Bush WS, Boston J, Pendergrass SA, Dumitrescu L, Goodloe R, Brown-Gentry K, Wilson S, McClellan B, Torstenson E, Basford MA, Spencer KL, Ritchie MD, Crawford DC,. Genetic association studies have rapidly become a major tool for identifying the genetic basis of common human diseases. The advent of cost-effective genotyping coupled with large collections of samples […]

Dana on Twitter

Fetch Tweets: Invalid or expired token. Code: 89

Affiliations

MetroHealthLogoCWRUlogowTag240x120

Curriculum vitae