DANA C. CRAWFORD, PH.D.
Assistant Director for Population and Diversity Research
Dana Crawford, Ph.D., is Associate Professor in the Departments of Population and Quantitative Health Sciences (primary) and Genetics and Genome Sciences (secondary) and Assistant Director for Population and Diversity Research in the Institute for Computational Biology. Dr. Crawford received her Ph.D. at Emory University in genetics and molecular biology in 2000 and then trained as a post-doctoral fellow as an Epidemic Intelligence Service Officer at the Centers for Disease Control and Prevention (2000–2002) and as a senior fellow at the University of Washington’s Department of Genome Sciences (2002–2006). Prior to her most current position, Dr. Crawford spent eight years as tenure-track faculty in Department of Molecular Physiology and Biophysics and Investigator in the Center for Human Genetics Research at Vanderbilt University. As a genetic epidemiologist at CWRU, Dr. Crawford’s broad research interests include applying genetic variation data to large-scale epidemiologic and clinical cohorts to better understand human genotype-phenotype associations with an emphasis on diverse populations.
Replication of associations between GWAS SNPs and melanoma risk in the Population Architecture Using Genomics and Epidemiology (PAGE) Study.
Kocarnik JM, Park SL, Han J, Dumitrescu L, Cheng I, Wilkens LR, Schumacher FR, Kolonel L, Carlson CS, Crawford DC, Goodloe RJ, Dilks H, Baker P, Richardson D, Ambite JL, Song F, Quresh AA, Zhang M, Duggan D, Hutter C, Hindorff LA, Bush WS, Kooperberg C, Le Marchand L, Peters U,.
Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies.
Mitchell SL, Hall JB, Goodloe RJ, Boston J, Farber-Eger E, Pendergrass SA, Bush WS, Crawford DC,. Mitochondria play a critical role in the cell and have DNA independent of the nuclear genome. There is much evidence that mitochondrial DNA (mtDNA) variation plays a role in human health and disease, however, this area of investigation has […]
Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia.
Park SL, Fesinmeyer MD, Timofeeva M, Caberto CP, Kocarnik JM, Han Y, Love SA, Young A, Dumitrescu L, Lin Y, Goodloe R, Wilkens LR, Hindorff L, Fowke JH, Carty C, Buyske S, Schumacher FR, Butler A, Dilks H, Deelman E, Cote ML, Chen W, Pande M, Christiani DC, Field JK, Bickebller H, Risch A, Heinrich […]
Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia.
Cheng I, Kocarnik JM, Dumitrescu L, Lindor NM, Chang-Claude J, Avery CL, Caberto CP, Love SA, Slattery ML, Chan AT, Baron JA, Hindorff LA, Park SL, Schumacher FR, Hoffmeister M, Kraft P, Butler AM, Duggan DJ, Hou L, Carlson CS, Monroe KR, Lin Y, Carty CL, Mann S, Ma J, Giovannucci EL, Fuchs CS, Newcomb […]
- Pendergrass, SA, Crawford, DC. Using Electronic Health Records To Generate Phenotypes For Research. Curr Protoc Hum Genet 2019; 100 (1): e80. PubMed PMID:30516347 PubMed Central PMC6318047.
- Restrepo, NA, Laper, SM, Farber-Eger, E, Crawford, DC. Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records. BMC Med Genomics 2018; 11 (Suppl 3): 70. PubMed PMID:30255811 PubMed Central PMC6157155.
- Crawford, DC, Restrepo, NA, Diggins, KE, Farber-Eger, E, Wells, QS. Frequency and phenotype consequence of APOC3 rare variants in patients with very low triglyceride levels. BMC Med Genomics 2018; 11 (Suppl 3): 66. PubMed PMID:30255797 PubMed Central PMC6156840.
- Fernández-Rhodes, L, Malinowski, JR, Wang, Y, Tao, R, Pankratz, N, Jeff, JM, Yoneyama, S, Carty, CL, Setiawan, VW, Le Marchand, L et al.. The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis. PLoS ONE 2018; 13 (7): e0200486. PubMed PMID:30044860 PubMed Central PMC6059436.
- Smieszek, S, Mitchell, SL, Farber-Eger, EH, Veatch, OJ, Wheeler, NR, Goodloe, RJ, Wells, QS, Murdock, DG, Crawford, DC. Hi-MC: a novel method for high-throughput mitochondrial haplogroup classification. PeerJ 2018; 6 : e5149. PubMed PMID:29967758 PubMed Central PMC6022720.
- Cooke Bailey, JN, Crawford, DC, Goldenberg, A, Slaven, A, Pencak, J, Schachere, M, Bush, WS, Sedor, JR, O'Toole, JF. Willingness to Participate in a National Precision Medicine Cohort: Attitudes of Chronic Kidney Disease Patients at a Cleveland Public Hospital. J Pers Med 2018; 8 (3): . PubMed PMID:29949895 PubMed Central PMC6164471.
- Crawford, DC, Bailey, JNC, Miskimen, K, Miron, P, McCauley, JL, Sedor, JR, ƠToole, JF, Bush, WS. Somatic T-cell Receptor Diversity in a Chronic Kidney Disease PatientPopulation Linked to Electronic Health Records. AMIA Jt Summits Transl Sci Proc 2018; 2017 : 63-71. PubMed PMID:29888042 PubMed Central PMC5961818.
- Jones, CC, Mercaldo, SF, Blume, JD, Wenzlaff, AS, Schwartz, AG, Chen, H, Deppen, SA, Bush, WS, Crawford, DC, Chanock, SJ et al.. Racial Disparities in Lung Cancer Survival: The Contribution of Stage, Treatment, and Ancestry. J Thorac Oncol 2018; 13 (10): 1464-1473. PubMed PMID:29885480 PubMed Central PMC6153049.
- Kocarnik, JM, Richard, M, Graff, M, Haessler, J, Bien, S, Carlson, C, Carty, CL, Reiner, AP, Avery, CL, Ballantyne, CM et al.. Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study. Hum. Mol. Genet. 2018; 27 (16): 2940-2953. PubMed PMID:29878111 PubMed Central PMC6077792.
- Gong, J, Nishimura, KK, Fernandez-Rhodes, L, Haessler, J, Bien, S, Graff, M, Lim, U, Lu, Y, Gross, M, Fornage, M et al.. Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 2018; 42 (3): 384-390. PubMed PMID:29381148 PubMed Central PMC5876082.