3rd Personalized Medicine Conference in Puerto Vallarta, Mexico (2019)

¡Hola Precision Medicine–Bienvenidos a México! The 3rd Personalized Medicine Conference, organized by Fusion Conferences Limited, was held May 30 – June 2, 2019 in Puerto Vallarta, Mexico. Chaired by Drs. Marylyn Ritchie, David Roth, and Mike Snyder, this two and a half day conference covered all things precision medicine, including sequencing, electronic health records, artificial […]

Mind the gap: resources required to receive, process and interpret research-returned whole genome data.

Crawford DC, Cooke Bailey JN, Briggs FBS,. Most genotype-phenotype studies have historically lacked population diversity, impacting the generalizability of findings and thereby limiting the ability to equitably implement precision medicine. This well-documented problem has generated much interest in the ascertainment of new cohorts with an emphasis on multiple dimensions of diversity, including race/ethnicity, gender, age, […]

Total Exposure Health, Bethesda, MD, September 6-7, 2018

For those of us trained in human genetics, we know that pretty much any trait or disease has a heritable component.  Yet, no matter how big, we also know heritability (additive genetics) is only part of story.  The environment, alone and in combination or interaction with genetics, and gene-gene interactions also affect phenotypes.  It’s complex, […]

One Million Genomes: From Discovery to Health, Keystone Symposia, Hannover, Germany, June 4-8, 2018

The little paper that could.  What that might be?  You know, that little project based on a small sample size that generated big opportunities.  Ever had one of those?  Well, we recently did. The “we” in this post was our MetroHealth/Institute for Computational Biology Pilot study, affectionately known as MIPs.  Collaborators Drs. John Sedor and […]

2018 Precision Genomics Midwest Conference

As you may or may not know, I organize the annual Cleveland Institute for Computational Biology (CICB) annual symposium, otherwise and affectionately known as the North Coast Conference on Precision Medicine (Figure 1).  I organized the first one-day symposium in 2015, and I was pretty proud of it as we were the only ones in […]

2018 NIH All of Us Research Priorities Workshop

Unless you have been living under a rock, you know that NIH has launched the largest effort to date to establish a cohort in the United States.  Chatter about the need for a nationally representative cohort bubbled up more than ten years ago in a commentary by Dr. Francis Collins (PMID:15164074), then head of the […]

2015 SACNAS, Washington, DC

SACNAS, Washington, DC, 2015 Genomic discovery, collaboration, and translation using electronic health records Narrative:  Precision medicine is often described as prescribing the right drug at the right dose the first time to each patient.  While the need for precision medicine is often acknowledged, the data and pathway to its implementation have been lacking.  Earlier this […]