SACNAS, Virtual, 2021 Quantitative Approaches to Understand Diseases with Electronic Health Record Data Session Description: Electronic Health Records (EHRs) capture information on a large number of people, including diverse and vulnerable individuals, and they can be used to conduct health studies. We will discuss various examples of how the quantitative disciplines of biostatistics, biomedical informatics and […]
Lidiette Angeles Perez University of Texas Southwestern Medical Center Dallas, TX Investigating the contributions of cerebellar-hippocampal circuitry to social behaviors, cognition, and dementia About 10% of the United States population will develop age-related dementias, disorders characterized by memory loss, social impairments, and behavioral changes. Despite their high prevalence and increasing cost, there is no effective […]
Sedelia Dominguez Washington State University Pullman, WA F. tularensis exploits AMPK activation to acquire host-derived nutrients Francisella tularensis, a highly virulent bacterial pathogen, causes tularemia in humans. In humans, tularemia leads to acute infections, but chronic infections result in bacteremia and have a high chance of being fatal. With a low infectious dose and potential […]
Natasha Lopes Fischer University of Pennsylvania Philadelphia, PA A Coxiella burnetii bacterial protein suppresses host NF-kB signalling Host immune cells use multiple strategies to detect and protect against microbial infections. Signalling pathways activated during infection play a central role in the innate immune response, as they enable the host cell to upregulate several antimicrobial programs. […]
The Case Western Reserve University Cleveland Institute for Computational Biology sponsored awards for graduate student oral presentations at the 2021 SACNAS Virtual National Diversity in STEM Conference. This year, three students qualified for our discipline: Natasha Lopes Fischer University of Pennsylvania A Coxiella burnetii bacterial protein suppresses host NF-kB signalling Sedelia […]
“This Cleveland center is uniquely positioned to contribute significantly to the national Alzheimer’s research agenda,” said Jonathan L. Haines, PhD, Department Chair, and Data Management and Statistics Core Leader for the Cleveland Alzheimer’s Disease Research Center (CADRC). The CADRC just received $15.4 million in continued NIH funding to support multi-institution collaborative research into Alzheimer’s disease […]
SACNAS, Virtual, 2020 Precisely Precision Medicine: A Primer on Translational Research Session Description: Precision medicine promises effective, tailored treatments for patients developed through diverse and representative population-level translational research. While the concept of precision medicine is not new, the convergence of modern-day genomics and electronic health records coupled with increased computational capacity has made the […]
Genomic Research Enabled by Electronic Health Records Dana C. Crawford, PhD Case Western Reserve University
Scott Williams, PhD, recently commented to Cleveland.com on various COVID-19 prediction models, and why models can vary. Some of the variation involves the availability of timely data and confidence in the data, given how quickly things are changing. Read the full story here.
Mark Cameron, PhD, was recently interviewed by Cleveland’s ABC affiliate, News 5, about COVID19, based on his experience with research colleagues in Toronto’s 2003 SARS outbreak. Watch the story here.