Thien Phan Texas A&M University School of Medicine Bryan, TX Impact of lymphangiogenesis on renal phosphate handling following kidney injury Thien Phan and Joseph M. Rutkowski Overconsumption of inorganic phosphate (Pi) increases renal dysfunction, tubular cell damage, and vascular calcification, hallmarks of kidney disease. Conversely, acute kidney injury (AKI) and chronic kidney disease (CKD) result […]

Evan Morrison University of Colorado Denver | Anschutz Medical Campus Denver, CO UBR4 mediates the quality control of a novel N-degron pathway Evan Morrison and Emma Larkin-Gero The open reading frame does more than merely encode a linear peptide sequence; it is a reservoir of regulatory information. The very beginning of the coding region plays […]

Manette Tanelus Virginia Polytechnic Institute and State University Blacksburg, VA But does it work? Evaluating the safety and immunogenicity of a novel Zika vaccine Manette Tanelus, Krisangel Lopez, Shaan Smith, John Muller, Dawn Auguste The flavivirus genus includes many mosquito-borne viruses of medical importance such as Yellow Fever virus, Dengue virus, and Zika virus. Zika […]

Yvonne Vasquez University of California Santa Cruz Santa Cruz, CA Comparative RNA sequencing analysis identifies therapeutic targets for children with difficult-to-treat cancers and leads to remarkable disease control in an ultra-rare tumor Childhood cancer outcomes have improved over the past few decades, but patients with difficult-to-treat tumors still fare poorly. Tumor DNA profiling reveals therapeutic […]

Rodolfo Corona Rodriguez University of California Berkeley Berkeley, CA Using Multi-view 3D Reconstruction for Understanding Descriptions of 2D Images Language provides a natural interface for humans to interact with robotic systems. Because robots are embodied in the world, they must be able to understand the links between language and their visual perception for this communication […]

Omar Lujano Olazaba San Diego State and University of California San Diego San Diego, CA The role of chemotherapy-induced fibrosis in the maintenance of tumor initiatingcells Ovarian cancer patients initially respond to cytotoxic chemotherapy but most relapse with chemoresistant disease. Research over the years supports the notion that tumor-initiating cells (TICs), a subpopulation of drug […]

Ester Álvarez Benedicto UT Southwestern Dallas, TX Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA) Lipid nanoparticles (LNPs) have been established as an essential platform for nucleic acid delivery. Efforts have led to the development of vaccines that protect against SARS-CoV-2 infection using LNPs to deliver messenger RNA (mRNA) […]

Elizabeth Delgado University of Michigan Ann Arbor, MI Distinct Wnt Signaling Thresholds Required for Polyposis in the Proximal and DistalStomach Familial adenomatous polyposis (FAP) is a genetic disorder characterized by the formation of precancerous polyps throughout the gastrointestinal tract. Polyps form in response to increased Wnt signaling caused by mutations in the adenomatous polyposis coli […]