The Case Western Reserve University Cleveland Institute for Computational Biology sponsored awards for graduate student oral presentations at the 2019 SACNAS The National Diversity in STEM Conference in Honolulu, Hawai’i. This year, three students qualified for our discipline: Melissa Roberts University of California, Berkeley A Genetic Strategy to Identify Lipid Droplet Protein Degradation Pathways Stephanie […]
Nicholas Carleson Oregon State University Corvallis, OR Gene Duplication, Pathogenicity, and Genome Plasticity of Phytophthora ramorum Nicholas Carleson*1; Brian Knaus1; Meredith Larsen2; Caroline Press2 and Niklaus Grünwald2, (1)Oregon State University, Department of Botany and Plant Pathology, (2)Horticultural Crops Research Laboratory, United States Department of Agriculture, Agricultural Research Service Clonally reproducing plant pathogens, that do […]
Stephanie L. Silva-Del Toro University of Iowa Iowa City, IA Mechanisms of H. Pylori-Induced Neutrophil Nuclear Hypersegmentation Stephanie L. Silva-Del Toro*, University of Iowa and Lee-Ann Allen, University of Iowa Inflammation Program Helicobacter pylori is a human pathogen that resides in the gastric mucosa, eliciting a neutrophil (PMN) dominant inflammatory response that can progress […]
Melissa Roberts University of California, Berkeley Berkeley, CA A Genetic Strategy to Identify Lipid Droplet Protein Degradation Pathways Melissa Roberts*1; Dara Leto2; Julian Stevenson1; Kartoosh Heydari1; Lawrence Bacudio1; Ron Kopito2; Michael Bassik2 and James Olzmann1, (1)University of California, Berkeley, (2)Stanford University Nearly all cells store lipids in endoplasmic reticulum (ER)-derived organelles called lipid droplets […]
Jonathan Haines, PhD, Department Chair, talked with National Public Radio about the challenges of recruiting diverse populations for genetic studies of Alzheimer’s Disease. Listen here:
Jill Barnholtz-Sloan, PhD, joined several faculty members for a CWRU THINK magazine feature highlighting the cancer research underway at Case Western Reserve University. Dr. Sloan’s focus is on using big data to better understand the mechanism of disease, its prevention, and treatment. “Having access to data from large sets of cancer patients beyond just your […]
People who participate in genetic research increasingly tell researchers that they want all of their genetic data back. But many of these participants do not have the data management infrastructure or analytical tools to interpret this information. And while third party companies eagerly offer to interpret results, they are unregulated and may offer incomplete or […]
Farren Briggs, PhD ScM, recently presented on the challenges of returning genetic data to individual research participants. In his presentation, Dr. Briggs cautioned his colleagues about even making the most general of assumptions regarding their research participants, including their access to the internet and computing infrastructure, and their digital literacy. This is compounded by the […]
Before becoming a member of the American Society of Human Genetics (ASHG) and attending the annual meeting, I was not all that familiar with San Diego. Sure, we had visited a time or two as kids, but geez, that was a long time ago. Now we go so often, San Diego seems like a second […]
For those of us trained in human genetics, we know that pretty much any trait or disease has a heritable component. Yet, no matter how big, we also know heritability (additive genetics) is only part of story. The environment, alone and in combination or interaction with genetics, and gene-gene interactions also affect phenotypes. It’s complex, […]
