Welcome to the Symposium Blog!

We have now organized two symposia focusing on big data and precision medicine topics with a third one in the works focusing on measuring exposures.  In an effort to sustain the dialog initiated by each of these events, we are hosting a blog on this website.  This blog will feature short opinion pieces and articles […]

Dr. Marylyn Ritchie and DiscovEHR

In biomedical research, “precision medicine” is the buzz-word or phrase du jour permeating the latest conference abstracts, manuscripts, and grant proposals.  Precision medicine is broadly defined as using a data-driven approach to offer tailored treatments or prevention strategies to patients.  The recent popularity of the precision medicine term is likely due to the 2015 White […]

Genomic newborn screening: public health policy considerations and recommendations.

The use of genome-wide (whole genome or exome) sequencing for population-based newborn screening presents an opportunity to detect and treat or prevent many more serious early-onset health conditions than is possible today.The Paediatric Task Team of the Global Alliance for Genomics and Health’s Regulatory and Ethics Working Group reviewed current understanding and concerns regarding the […]

Recent Reflections

We are well into 2017, and I have yet to post an update on the lab’s accomplishments as of the end of 2016.  If you were a human being like the rest of us living in 2016, you probably feel the same as many of us about that year.  It was a year very much […]

Faculty positions available at CWRU

We have a trio of open faculty positions available here at CWRU.  The positions are within the Department of Epidemiology and Biostatistics, with some having the opportunity for an additional appointment in the Institute of Computational Biology: Tenure-Track/Tenured Faculty with Expertise in Biomedical Data Science Tenure-Track/Tenured Faculty Position in Cancer Epidemiology Director of the MPH […]

American Society of Human Genetics (ASHG) 2016 in Vancouver, Canada

This year’s American Society of Human Genetics (ASHG) was held—where else?—in Vancouver, Canada!  Our northern neighbors invited human geneticists far and wide for five days of presentations, networking, and some scientific fun. Of course, I hardly ever pass up the opportunity to attend this meeting.  As I have written before, ASHG is a great place […]

Gordon Research Conference 2016, Human Single Nucleotide Polymorphisms & Disease, Mount Holyoke College

As I alluded in my previous post, I was invited to give talks at two prestigious meetings this year.  The second meeting was the Gordon Research Conference Human Single Nucleotide Polymorphisms & Disease conference “Understanding the Mechanisms of Variant Effects in the Era of Genome Sequencing” held at Mount Holyoke College in South Hadley, Massachusetts […]

Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses.

Recent studies indicate that mitochondrial proteins may contribute to the pathogenesis of primary open-angle glaucoma (POAG). In this study, we examined the association between POAG and common variations in gene-encoding mitochondrial proteins.We examined genetic data from 3430 POAG cases and 3108 controls derived from the combination of the GLAUGEN and NEIGHBOR studies. We constructed biological-system […]