The little paper that could. What that might be? You know, that little project based on a small sample size that generated big opportunities. Ever had one of those? Well, we recently did. The “we” in this post was our MetroHealth/Institute for Computational Biology Pilot study, affectionately known as MIPs. Collaborators Drs. John Sedor and […]
An international study analyzing data from more than 94,000 people identified five new genes related to Alzheimer’s disease. The study also supports developing evidence that groups of genes associated with specific biological processes serve as genetic “hubs” that play an important role in the disease process. Funded in part by the National Institute on Aging […]
What can I say–this end-of-the-year update is extremely late. I mean, it’s February and 2019 is well underway. I blame it on the polar vortex. Actually, this was supposed to be a 2018 summer update, so it is not fair to blame the CLE winter for my tardiness. Ah, summer (Figure 1). Where did you […]
Chun Li, PhD, secures NIH grant to expand work on novel statistical methods In collaboration with Vanderbilt University Medical Center, CWRU researcher is developing techniques applied to the study of complex, chronic health conditions Cleveland, Ohio – A woman diagnosed with HIV works with her care team who consider many variables in tailoring a treatment […]
As you may or may not know, I organize the annual Cleveland Institute for Computational Biology (CICB) annual symposium, otherwise and affectionately known as the North Coast Conference on Precision Medicine (Figure 1). I organized the first one-day symposium in 2015, and I was pretty proud of it as we were the only ones in […]
Unless you have been living under a rock, you know that NIH has launched the largest effort to date to establish a cohort in the United States. Chatter about the need for a nationally representative cohort bubbled up more than ten years ago in a commentary by Dr. Francis Collins (PMID:15164074), then head of the […]
Dr. Jill Barnholtz-Sloan presented her research on Leveraging big data for impact on Brain Tumor research at the 2018 Society for NeuroOncology Annual Meeting in New Orleans, LA.
Dr. Jill Barnholtz-Sloan presented her research on Sex-Specific differences in incidence, survival, and risk factors for brain tumors at the 2018 Society for NeuroOncology Annual Meeting in New Orleans, LA.
SACNAS, San Antonio, TX, 2018 The Importance of Diversity in Precision Medicine Research Narrative: National efforts are underway to ascertain one million participants for precision medicine research and an intense interest in ensuring this cohort is diverse across multiple dimensions. We provide here an overview of the importance of diversity in precision medicine research highlighting […]
Melissa Spear University of California, San Francisco San Francisco, CA The Role of Recent Demography in Shaping Patterns of Genetic Variation in US Hispanic/Latino Populations Melissa Spear, Biomedical Sciences Graduate Program, Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, Dara Torgerson, , Department of Pediatrics, University of California, San Francisco and […]
It’s official—the All of Us Research Program launched on May 6, 2018. For those of you unfamiliar with the All of Us Research Program, formerly known as the Precision Medicine Initiative Cohort Program, it is an ambitious effort to recruit at least one million participants in the the United States for precision medicine research. Recruitment […]